摘要
目的 探讨子宫腺瘤样瘤的组织发生、临床病理特征及鉴别诊断。方法 对 11例子宫腺瘤样瘤的资料 ,进行综合分析 ,光镜观察。其中 6例进行免疫组化标记。结果 年龄 2 1～ 5 8岁 ,临床表现无特征性 ,肿瘤好发子宫角、宫底处。光镜下表现为上皮样细胞形成腺样、腔隙、条索样结构 ,有些上皮样细胞可呈空泡状、印戒样。大多伴有平滑肌瘤或平滑肌增生。免疫组化 :CK、EMA、VIM、Calretinin均阳性表达 ,而FⅧ因子相关抗原、CEA均阴性。结论 子宫腺瘤样瘤是一种良性病变 ,符合间皮来源 ,尤其注意的是 :此瘤出现以空泡、印戒样细胞为主时 ,易误诊为腺癌或印戒细胞癌 ,结合免疫标记 ,可鉴别之。
Objective To study the histogensis,clinical pathological characters and differential dioganosis of uterine adenomatoid tumor.Methods Eleven cases of adenomatoid tumor were comprehensive analysized and observed microscopically and 6 cases of them were marked by immunohistochemical method.Results The age of the patients ranged from 21 to 58 years and the clinical characters were not appearant.The predilection sites of the tumor were the fundus or corner of uterus.Micorsopical manifestations showed that epithelioid cells formed adenoid,lacuna,streak structure,some epithelioid cells became vacuolated or signet-ring like.Majority of the tumors accompanied by liomyoma or hyperlasia of smooth muscle.Immunohistochemical method showed that CK,EMA,VIM,Calretinin expressed positively while FⅧ RAg,CEA expressed negatively.Conclusion Adenomatoid tumor is a kind of benign tumor of uterine and originated from mesothelium tissue.Especiallywhile the vacuolated or signet-ring cell occurred,it was easily misdiagnosed as adenocarcinoma or signet-ring carcinoma.Immunohistochemistry is a method to differentiate them.
出处
《中国基层医药》
CAS
2003年第6期527-528,共2页
Chinese Journal of Primary Medicine and Pharmacy
关键词
子宫腺瘤样瘤
鉴别诊断
临床病理特征
误诊
免疫组织化学
Uterine tumor Adenomatoid tumor Immunohistochemistry Clinical pathology Differential diagnosis
