摘要
目的采用氟西汀(百优解)治疗脑卒中后抑郁症(PSD),观察百优解对PSD的疗效。方法PSD患者63例,按入院先后顺序随机分为2组,百优解治疗组42例,对照组21例。对照组给予常规脑血管病治疗,治疗组在此基础上加用百优解20mg,1次/d,连续口服4周。于治疗前后分别进行汉密顿(HAMD)评定量表、改良爱丁堡-斯堪的那维亚卒中量表(MESSS)评分进行评估。结果治疗组总有效率81.0%,对照组总有效率23.8%,经统计学处理有显著性差异(χ2=37.63,P<0.01)。结论氟西汀治疗卒中后抑郁症的效果较好,不但能改善患者的抑郁症状,还有利于患者神经功能缺损的康复。
Aim To study the effect of Fluoxine on post-stroke depres-sion(PSD).Methods Sixty-three patients with PSD were r andomly divided into two groups:Fluoxine treatment group(n=42)and control group(n=21).The scores of HAMD(Hamilton Depresion)and MESSS(Modify Ed-ingberg scandine Stroke Scale)in the two groups were compared.Results The effective rates of the treatment and control groups were 80.9%and23.81%respectively,with signific ant differences between the two grou ps(χ 2 =27.63,P<0.01).Conclusion Fluoxine not only inhibits depres-sive symptoms but also helps to function recovery of patients,which sign s that fluoxine has a better effect on P SD.
出处
《中国临床康复》
CSCD
2003年第13期1924-1925,共2页
Chinese Journal of Clinical Rehabilitation
关键词
氟西汀
治疗
急性脑卒中
抑郁症
临床观察
百优解
fluoxetine
cerebrovascular accid ent
depressive disorder
treatment outcome
