摘要
目的观察一个社区居住的老年人群体血压水平与认知功能的关系。方法在北京市≥60岁的老年人中抽取一个样本,对其进行认知功能和血压的流行病学调查。结果2617名≥60岁老人的平均收缩压139.38±23.28mmHg,平均舒张压80.28±12.02mmHg,平均MMSE得分22.99±5.94分。MMSE异常525人,占20.1%。收缩压及舒张压高的老人认知异常的比例显著增高,分层分析提示:在女性、低教育程度、低龄老人及未坚持高血压治疗的老人中,不同血压水平对认知功能改变有显著影响,血压水平高者认知异常的发生率增高,这种关系在排除脑血管病的因素后依然存在。结论北京社区老年人高的收缩压及舒张压水平对认知功能均有损害。
Objective To observe the association between blood pressure and cognition of the elderly in Beijing. Methods 2617 community residents aged 60 and over were measured blood pressure and were tested with short mental test of Mini-Mental State Examination(MMSE). Results The mean systolic blood pressure, diastolic blood pressure and MMSE score were 139.38±23.28mmHg,80.28±12.02mmHg and 22.99±5.94mmHg respectively. 525 elderly were abnormal in MMSE, about 20.1%of the total sample. The elderly who had elevated systolic blood pressure and diastolic blood pressure had a higher ratio of cognitive impairment. The difference was statistically significant. Further stratified observation showed that elderly with elevated blood pressure, low educational level,relatively young elderly and without persistent antihypertensive medication were more commonly seen in cognitive impairment. Increased incidence of cognitive impairment was found in those with increased level of hypertension. The fact that elderly male with elevated systolic blood pressure and elderly female with diastolic blood pressure were prone to have cognitive impairment was clinically significant. Conclusions Elevated systolic blood pressure and diastolic blood pressure were harmful to cognitive function in the elderly.
出处
《老年医学与保健》
CAS
2003年第2期96-98,113,共4页
Geriatrics & Health Care
