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缺氧诱导因子1与缺氧信号转导机制 被引量:15

Hypoxia-inducible factor 1 and mechanisms of hypoxia signal transduction
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摘要 缺氧诱导因子 1(HIF 1)不仅作为维持氧自稳平衡的核心调控因子 ,调控一系列缺氧相关基因的表达 ,而且在感受缺氧 ,传递缺氧信号的过程中发挥重要作用。氧依赖的羟化酶的发现 ,证明胞内氧浓度直接调控HIF 1α亚基的表达 ,为揭示缺氧信号调控HIF
出处 《生理科学进展》 CAS CSCD 北大核心 2003年第2期169-170,共2页 Progress in Physiological Sciences
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  • 1叶红,金咸瑢.低氧诱导因子-1的结构、功能、调节及其与低氧信号转导的关系[J].生理科学进展,2001,32(1):62-64. 被引量:24
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