摘要
目的 探讨急性脑血管病 (acutecerebrovasculardisease ,ACVD)患者血清心肌酶谱改变及其临床意义。方法 于发病 7天内检测 79例ACVD患者血清心肌酶谱 ,即天门冬氨酸氨基转移酶 (AST)、乳酸脱氢酶 (LDH)、α 羟丁酸脱氢酶 (α HBDH)、肌酸激酶 (CK)和心肌型肌酸激酶同功酶 (CK MB) ,同时进行神经功能缺损程度评分 (SSS) ,与32例对照组对比分析。结果 除CK MB外 ,脑出血 (ICH)组和脑梗死 (CI)组的血清心肌酶谱均高于对照组 (P <0 .0 5 ) ;ICH组和CI组的血清心肌酶谱比较无统计学意义 (P >0 .0 5 ) ;有颞叶损害组心肌酶谱高于无颞叶损害组 (P<0 .0 5 ) ;LDH水平与SSS评分呈正相关 (rs=0 .30 3,P <0 .0 1)。结论 ACVD患者存在明显的心肌酶谱改变 。
Objective To observe the changes and the clinical significance in serum myocardial zymogram of patients with acute cerebrovascular disease (ACVD).Methods To estimate the serum myocardial zymogram,viz.aspartate aminotransferase (AST),lactate dehydrogenase (LDH),α hydroxybutyrate dehydrogenase (α HBDH),creatine kinase (CK) and its MB isoenzyme (CK MB) of 79 patients with ACVD in 7days,and to assess their neurologic impairment by the Scandinanvian Stroke Scale (SSS) at the same time,then to make comparison with control group.Results Except CK MB,the serum myocardial zymogram of intracerebral hemorrhage (ICH) group and cerebral infarction (CI) group were both higher than that of control group (P< 0.05 ).Comparing ICH group with CI group,no significant differences could be found in the serum myocardial zymogram of two groups (P> 0.05 ).The serum myocardial zymogram of group with temporal lobe damage were higher than those of group without temporal lobe damage (P< 0.05 ).Positive correlation was shown between LDH level and SSS score (r s= 0.303 ,P< 0.01 ).Conclusions There are significant changes in the serum myocardial zymogram of patients with ACVD.Serum myocardial zymogram is helpful to judge patient's state and prognosi.
出处
《临床荟萃》
CAS
北大核心
2003年第13期742-744,共3页
Clinical Focus
