摘要
目的探讨茵栀黄口服液联合蓝光照射治疗新生儿黄疸的临床疗效。方法选取2014年6月—2015年6月苏州市立医院收治的新生儿黄疸患儿85例,按随机数字表法分为对照组40例与研究组45例。对照组患儿予以蓝光照射治疗,研究组患儿在对照组基础上加用茵栀黄口服液治疗。观察两组患儿临床疗效、治疗前及治疗后7d血清胆红素水平、血清胆红素水平恢复正常时间、住院时间及不良反应发生情况。结果研究组患儿总有效率高于对照组,差异有统计学意义(P<0.05);治疗前两组患儿血清胆红素水平比较,差异无统计学意义(P>0.05),治疗后7d研究组患儿血清胆红素水平低于对照组,差异有统计学意义(P<0.05);研究组患儿血清胆红素水平恢复正常时间、住院时间短于对照组,差异有统计学意义(P<0.05);研究组患儿不良反应发生率高于对照组,差异有统计学意义(P<0.05)。结论茵栀黄口服液联合蓝光照射治疗新生儿黄疸的临床疗效显著,可促进血清胆红素水平恢复,缩短患儿住院时间。
Objective To explore the effect of Yinzhihuang oral liquid and blue light irradiation in treating neonatal jaundice. Methods A total of 85 children with neonatal jaundice were selected in the Suzhou Municipal Hospital from June 2014 to June 2015,according to random number table,they were divided into control group 40 cases and study group 45 cases. Control group were given blue light irradiation treatment,study group were given Yinzhihuang oral liquid on the basis of control group. Clinical effect,serum bilirubin level before treatment and after treatment of 7 days,serum bilirubin restored normal time,hospitalization time and incidence of adverse reactions between the two groups were compared. Results The total effec-tive rate of study group was higher than that of control group(P < 0. 05);before treatment,serum bilirubin level showed no significant differences between the two groups(P > 0. 05),after treatment of 7 days,serum bilirubin level of study group was lower than that of control group( P < 0. 05);serum bilirubin restored normal time,hospitalization time of study group were shorter than those of control group(P < 0. 05);incidence of adverse reactions of study group was lower than that of control group(P < 0. 05). Conclusion Yinzhihuang oral liquid and blue light irradiation have notable curative effect in the treatment of neonatal jaundice,can promote the serum bilirubin level recovery,shorten the length of hospital stay.
出处
《临床合理用药杂志》
2015年第36期20-21,共2页
Chinese Journal of Clinical Rational Drug Use
关键词
黄疸
新生儿
茵栀黄口服液
治疗结果
Jaundice,neonatal
Yinzhihuang oral liquid
Treatment outcome
