摘要
目的比较4种不同方案治疗流行性感冒的有效性和安全性。方法选择医院门诊收治的流行性感冒患者244例,根据用药方案不同分为A组66例、B组57例、C组61例、D组60例。4组均给予利巴韦林治疗,在此基础上,A组给予板蓝根颗粒治疗,B组给予连花清瘟胶囊治疗,C组给予小柴胡颗粒治疗,D组给予蒲地蓝消炎口服液治疗。采用药物经济学分析比较4组的成本—效果分析。结果 A组、B组、C组、D组成本分别为48.31元/人、52.65元/人、67.83元/人、71.78元/人,治疗效果分别为45.45%、49.12%、60.66%、45.00%。敏感度分析显示,4种治疗方案受主要参数变化影响不大。结论连花清瘟胶囊方案为治疗流行性感冒的最佳方案。
Objective To compare the efficacy and safety of four different regimens in the treatment of influenza.Methods 244 outpatients with influenza in the hospital were selected,according to different medication regimens,they were divided into group A(66 cases),group B(57 cases),group C(61 cases),and group D(60 cases).4 groups were treated with ribavirin,on the basis of this,group A was treated with Banlangen granules,group B was given Lianhua Qingwen capsules,group C was given Xiaochaihu granules,and group D was given Pudilan Xiaoyan oral liquid.The cost-effectiveness of the four groups was compared using pharmacoeconomic analysis.Results The cost of group A,group B,group C and group D was 48.31 yuan/person,52.65 yuan/person,67.83 yuan/person,71.78 yuan/person,respectively.The therapeutic effects was 45.45%,49.12%,60.66%,and 45.00%,respectively.Sensitivity analysis result demonstrated parameter variation had no significant influence on these four regimens.Conclusion Lianhua Qingwen capsule is the best regimen for treating influenza.
作者
旷湘楠
KUANG Xiangnan(Yiling Hospital,Hebei Province,Shijiazhuang 050091,China;不详)
出处
《临床合理用药杂志》
2019年第22期6-7,共2页
Chinese Journal of Clinical Rational Drug Use