摘要
目的 探讨测定脐血胆红素和经皮胆红素 (TcB)在早期预测新生儿高胆红素血症中的应用价值。方法 测定 1 0 0例足月新生儿脐血胆红素浓度 ,并用经皮胆红素测定仪 (TcBM)动态监测经皮胆红素指数 (TcBI)的变化。结果 发生新生儿高胆红素血症 39例(39.0 % ) ,脐血胆红素浓度、生后 2 4 ,48,72h的TcBI,高胆红素血症组明显高于非高胆红素血症组 ,二组间差异有高度显著性 (P <0 .0 1 )。当脐血胆红素 <42 .8μmol/L、≥ 42 .8μmol/L、生后 2 4hTcBI≥ 1 6、48hTcBI≥ 1 8时 ,高胆红素血症发生率分别为 2 6 .3 %、79.2 %、77.3 %、80 .8%。结论 脐血胆红素浓度测定和动态监测TcB能早期预测新生儿高胆红素血症 ,为早期诊断和治疗提供可靠依据。
Objective To approach the practical value of cord blood bilirubin and transcutaneous bilirubin (TcB) in early diagnosis of neonate hyperbilirubinemia. Methods Assay of cord blood bilirubin and dynamic testing of TcB index(TcBI) in TcBmeter(TcBM) were performed in 100 natural term neonates. Results 39 neonates suffered hyperbilirubinemia( 39.0 %). Cord bilirubin and TcBI of 24, 48 and 72h postborn in hyperbilirubinemia group were statistically higher than that of non-hyperbilirubinemia group (P<0.01). In neonates when cord bilirubin<42.8μmol/L, ≥42.8μmol/L, TcBI 24h postborn≥16 and TcBI 48h postborn≥18, occurrence of hyperbilirubinemia were 26.3%, 79.2%, 77.3% and 80.8%, respectively. Conclusion Determination of cord bilirubin and dynamic testing of TcB could predict neonate hyperbilirubinemia in early stages and provide solid evidence for early diagnosis and treatment.
出处
《中国煤炭工业医学杂志》
2003年第7期599-600,共2页
Chinese Journal of Coal Industry Medicine
关键词
高胆红素血症
新生儿
脐血
胆红素
TcB
预测
测定
临床应用
cord blood bilirubin
transcutaneous bilirubin
early diagnosis
neonate
hyperbilirubinemia
