摘要
目的 :探讨上颌窦腺样囊性癌 (ACC)的诊断及手术加术后放疗的治疗效果 ,并分析与预后有关的因素。方法 :回顾性分析 1992～ 1999年 14例上颌窦ACC患者的临床资料 ,用Kaplan Meier法计算 5年及 10年无瘤生存率。结果 :随访 3～ 10年 ,平均 6 7.2个月。T2 N0 M0 2例 ,健在 ,无复发及转移 ;T3 N0 M0 4例 ,其中 1例术后5 7个月复发 ,3例健在 ,无复发及转移 ;T4N0 M0 8例 ,其中 2例术后分别于 36个月、4 0个月因局部复发、颅内侵犯死亡 ,1例术后 39个月复发 ,1例术后 96个月全身转移 ,4例健在 ,无复发及转移。 5年无瘤生存率为 72 .5 % ,10年无瘤生存率为 5 4 .4 %。结论 :上颌窦ACC早期症状不典型 ,容易误诊和漏诊 ;彻底的手术切除加术后放疗可以降低术后复发的机会 ,提高治愈率。
Objective:To investigate characteristic clinical features and outcomes for patients with adenoid cystic carcinoma of the maxillary sinuses (ACC).Method:Thirteen patients with ACC were treated with a combination of surgery and radiation. Prognostic factors were retrospectively analyzed. Result:The most frequent cause of failure was local recurrence at the primary site. There was no neck node failure. 1 patient experienced distant metastases after the treatment. The overall disease free survival rate at 5 years and 10 years were 72.5 % and 54.4 %, respectively.Conclusion:The symptoms of the ACC occurred in the maxillary sinuses are not specific. The early diagnoses are usually difficult. Surgeries combined with postoperative radiation are recommended for optimal local control and survival. The prognostic factors include the clinic stages of the tumor and the resection margins.
出处
《临床耳鼻咽喉科杂志》
CSCD
北大核心
2003年第8期466-467,共2页
Journal of Clinical Otorhinolaryngology
关键词
上颌窦肿瘤
囊腺癌
放射疗法
外科手术
Maxillary sinusneoplasms
Cystadenocarcinoma
Radiotherapy
Surgery
