摘要
目的 :观察昼夜节律对大鼠血液流变学的影响。方法 :SD大鼠 2 0只 ,按完全随机化分为两组 :白天组 1 1只 (采血时间在上午 9:0 0~ 1 0 :0 0 ) ;夜间组 9只 (采血时间在晚上 9:0 0~ 1 0 :0 0 )。流变学指标采用 NXE- 1型锥板式粘度计检测 ;检测温度 2 5℃。结果 :夜间组与白天组比较 ,夜间组的ηb(m Pa· s,2 2 5 s- 1 )、ηb(m Pa· s 1 1 .2 5 s- 1 ) ,均比白天组为低 (P<0 .0 5) ,而红细胞压积、ηb(1 1 .2 5 s- 1 ) /ηb(2 2 5 s- 1 )差异无显著性 (P>0 .0 5)。结论 :昼夜节律对
Objective:To observe the effect of circadian rhythm on hemorrheology of rats Methods:Twenty SD rats were randomly divided into 2 groups:day group( n =11)taken blood sample at 9~10 o'clock in the morning,and night group( n =9)at 9~10 o'clock in the night Hemorrheological parameters were detected with core and plate viscometer Results:The rates of low shear and hight shear in night group were lower than those in day group,while hematocrit and ratio of low shear and hight shear were no difference in between two groups Conclusion:There exists an effect of circadian rhythm on hemorrheology of rats
出处
《广东医学院学报》
2002年第3期175-176,共2页
Journal of Guangdong Medical College
关键词
昼夜节律
大鼠
血液流变学
影响
hemorrheology
blood viscosity
circadian rhythm
normal value
SD rat