摘要
①目的 探讨进展期胃癌及结肠癌根治术后腹腔化疗期腹腔灌洗液中癌胚抗原 (CEA)浓度变化的临床意义。②方法 对 1 999～ 2 0 0 0年收治的 60例胃癌及结肠癌根治术后病人常规行腹腔化疗 ,第 1、3、6月每次化疗前测定腹腔灌洗液CEA的浓度 ,所有病人均随访 1 .5～ 2 .0年。③结果 60例病人中 1 2例复发 ,复发组第 6月腹腔灌洗液CEA的浓度明显高于未复发组 (t=1 6 .58,P <0 .0 1 ) ,而第 1、3月两组CEA的浓度差别无显著意义(t=0 .43、0 .2 2 ,P >0 .0 5)。
Objective\ To evaluate the clinical significance of the changes of carcinoembryonic antigen(CEA) levels in peritoneal washings during chemotherapy for cancer of stomach or colon postoperatively.\ Methods\ Sixty patients underwent radical operations for the diseases mentioned above during the period of 1999 to 2000 were enrolled for intra abdominal chemotherapy. In months 1, 3 and 6, CEA was detected before chemotherapy was carried out. All the patients were followed up from 1.5 to 2.0 years.\ Results\ Twelve patients were found to have recurrence. The CEA levels in washings of month 6 was significantly higher in the recurrence group than that of non recurrence group ( t =16.58, P <0.01) and it was no significant difference in months 1 and 3 in terms of CEA levels( t =0.43, 0.22, P >0.05).\ Conclusion\ Detection of CEA levels in peritoneal irrigation fluid is of great value in prediction of abdominal recurrence.
出处
《齐鲁医学杂志》
2003年第2期126-127,共2页
Medical Journal of Qilu
关键词
胃癌
结肠癌
术后
腹腔灌洗液
癌胚抗原
检测
临床意义
gastric neoplasms
colorectal neoplasms
peritoneal irrigation fluid
carcinoembryonic antigen
