摘要
目的 观察克银I号胶囊对进行期寻常型银屑病患者临床症状、外周血T淋巴细胞亚群、表皮长生因子 (EGF)含量的影响 ,以及免疫球蛋白、淋巴细胞转化率的变化。方法 治疗组 2 6 0例口服克银I号胶囊 ,对照组15 0例口服复方青黛丸 ,2组均治疗 2个月。结果 2组临床疗效比较 ,治疗组明显高于对照组 (P <0 .0 1) ;治疗后治疗组EGF含量下降明显 ,与对照组比较有显著性差异 (P <0 .0 1) ;治疗组治疗后CD4细胞水平较对照组治疗后高 ,有显著性差异 (P <0 .0 1) ;治疗组与对照组比较 ,治疗后IgG、IgA水平下降具显著性差异 (P <0 .0 1) ;治疗组治疗后淋巴细胞转化率恢复至正常范围 ,对照组仍低于正常 ,2组比较有显著性差异 (P <0 .0 1)。结论 克银Ⅰ号胶囊能改善进行期寻常型银屑病的临床症状 ,使皮损区EGF含量下降 ,以及提高人体免疫功能。
Objective To observe the effects of No.I Keyin capsules on the clinical symptoms, T lymphocyte subpopulation, the content of epidermal growth factor (EGF), immunoglobulin and lymphocyte transformation rate in patients with psoriasis vulgaris. Methods 260 patients in treatment group were administered orally with No.I Keyin capsules;150 patients in control group were administered orally with compound Qingdai pill, with a treatment course of two months for both groups. ]WTHZ]Results WTHZ]Results Results The therapeutic effect in treatment group was significantly higher than that in control group (P<0.01);after treatment the content of EGF in treatment group was obviously decreased, as compared with that in control group (P<0.01); after treatment the level of CD4 in treatment group was significantly increased, as compared with that in control group (P<0.01); after treatment the level of IgG and IgA in treatment group was obviously decreased, as compared with that in control group (P<0.01); the lymphocyte transformation rate in treatment group after treatment was significantly higher than that in control group (P<0.01). Conclusion No.I keyin capsules can improve the clinical symptoms of patients with psoriasis vulgaris, decrease the content of EGF and increase the immunological function of organism.
出处
《河北中医》
2003年第8期567-569,共3页
Hebei Journal of Traditional Chinese Medicine
