摘要
目的 :观察前列地尔治疗老年急性重症胆管炎 (ACST)的疗效。方法 :ACST患者 96例 ,均给予抗休克、抗感染和手术治疗 ,其中治疗组 5 0例 ,同时加用前列地尔注射液 10 μg于 0 .9%氯化钠注射液 10mL中 ,iv ,qd ,疗程 1周 ;对照组 46例 ,给予全肠外营养。结果 :治疗组疗效优于对照组 ,血浆蛋白升高明显 ,严重并发症发生率和病死率低 ,两组均差异有显著性 (P <0 .0 5 )。结论 :前列地尔联合全肠外营养是治疗老年ACST重要的、有效的支持方法。
Objective:To observe the effects of alprostadil in the treatment of acute cholangitis of severe type(ACST) in the elderly. Methods:96 patients with ACST in the elderly were randomly divided into two groups treated with alprostadil and total parenteral nutrition(TPN). Patients in the treatment group (50 cases) were given each a daily dose of 10 μg of alprostadil which was added to 10 mL of 0.9% sodium chloride by intravenous for a week. TPN was used for patients of the control group 46 cases. All patients were given the treatment of anti-shock, antibiotic and operation. Albumen in the blood was determined, the incidence of severe complication and mortality were recorded before and after the treatment. Results:The effects of the treatment group are superior to those of the control group. Patients with alprostadil and TPN had significant lower morbidity rate and lower risk of the severe complication than those with only TPN. The difference was statistically significant( P <0.05). Conclusion:Alprostadil combined with TPN is an effective treatment for ACST in the elderly.
出处
《医药导报》
CAS
2003年第9期606-607,共2页
Herald of Medicine
关键词
前列地尔
全肠外营养
胆管炎
重症
急性
Alprostadil
Total parenteral nutrition
Acute cholangitis of severe type
