摘要
目的 :探讨尿酸 (UA)、β2-微球蛋白(β2-MG)对重度妊高征围产期结局的影响。方法 :测定51例重度妊高征患者血清UA、β2-MG、尿素氮 (BUN)、肌酐(Cr)水平和尿蛋白定量 ,统计孕期及新生儿情况 ,按围产儿存活与否分为死亡组与存活组进行分析。结果 :(1)死亡组前3个指标明显高于存活组 ,尿蛋白定量2组差异无统计学意义。(2)血清UA水平与BUN、β2-MG水平呈正相关 ,与新生儿体重呈负相关。结论 :监测重度妊高征患者血压、尿蛋白、尿素氮、肌酐的同时更应密切监测尿酸和β2-MG的变化 。
Objective:To study the clinical significance of monitoring UA andβ 2 -MG on peripartum outcome in severe pregnancy induced hypertension(PIH).Methods:Fifty one patients with severe PIH were divided into a neonatal death group(group D)and a neonatal survival group(group S).Their levels of serum UA,β 2 -MG,BUN,Cr and urinary protein(UP)were tested.Results:(1)The levels of serum UA,β 2 -MG,BUN and Cr in the group D were significantly higher than those in the group S,but there was no difference in the level of UP beˉtween the two groups.(2)The levels of serum UA was positively correlative with the levels of BUN andβ 2 -MG and negatively correlative with the weight of infants.Conclusion:Beside the levels of blood pressure,UP,BUN and Cr,the levels of UA andβ 2 -MG should be monitored so as to direct the clinical diagnosis and treatment.
出处
《天津医药》
CAS
北大核心
2003年第7期441-442,共2页
Tianjin Medical Journal
关键词
重度妊高征
血清
尿酸
Β2-微球蛋白
监测
围产期结局
pregnancy complications,cardiovascular hypertension uriacid beta-microglobulin fetal growth retardation prognosis
