摘要
目的 明确胆囊癌和胆囊结石之间的相关关系。方法 回顾性调查了全国 2 8个省市的 392 2例胆囊癌 ,结合病例对照方法研究胆囊结石的病程 ,胆囊结石大小和胆囊癌的关系。结果 ( 1)胆囊癌合并胆囊结石的发生率为 46.7% ,胆囊癌伴发胆囊结石的相对危险度为 13.7。 ( 2 )合并胆囊结石的病程平均为 10~ 15年。 ( 3)胆囊结石直径大于 3cm比结石直径在 1cm内的风险高 8.8倍。结论 直径大于 3cm ,病程达 10~ 15年的胆囊结石是胆囊癌发生的高危险因素 。
Objective To investigate the relationship between the gallbladder cancer and gallstone.Methods A total of 3 922 cases of gallbladder cancer from 28 provinces of China were reviewed.Using the case control study,the relationship between the size of gallstones,the course of gallbladder cancer and gallbladder carcinoma were analyzed.Results (1)gallstones were found in 46.7% with the cases of gallbladder cancer,the relative risk (RR) of gallbladder cancer with gallstones was 13.7.(2) the average course with gallstones was 10~15 years.(3)the risk in the patients with gallstone of 3 cm in diameter or above was 8.8 times higher than those with gallstone be low 1 cm.Conclusions It is higher risk when the gallstone is 3 cm in diameter or above,and the course is 10~15 years.We suggest that cholecystectomy should be recommended to these patients.
出处
《临床外科杂志》
2003年第4期214-215,共2页
Journal of Clinical Surgery
关键词
胆囊癌
胆囊结石
gallbladder cancer
gallstone