摘要
目的 :探讨原发性阴道癌的治疗方式及预后因素。方法 :196 3年— 1997年间 ,我院收治了原发性阴道癌 92例 ,0期 4例 , 期 2 2例 , 期 35例 , 期 18例 , 期 13例。鳞癌 72例 ,腺癌2 0例。手术治疗者 2 9例 ,放射治疗者 5 6例。结果 :总的 5年生存率为 4 8.9% , 期、 期患者行手术治疗者的 5年生存率为 5 0 .1% ,行放射治疗者的 5年生存率为 70 .3% ,二者无显著的统计学差异 (P= 0 .17)。单因素分析示期别、肿瘤大小、病理类型及阴道受侵长度为预后因素 (P<0 .0 5 )。多因素分析示期别、肿瘤大小及阴道受侵长度为独立预后因素。结论 :原发性阴道癌的治疗首选放疗 ,早期病例可选择手术治疗。独立的预后因素有分期、肿瘤大小及阴道受侵长度。
Objective:To explore the therapy methods and prognostic factors of primary vaginal carcinoma.Methods:From 1963 to 1997, 92 cases of primary vaginal carcinoma were treated, stage 0～4 cases, stageⅠ～22 cases, stageⅡ～35 cases, stage Ⅲ～18 cases, stage Ⅳ～13 cases. 29 cases were treated by operation, 56 cases were treated by radiation.Results:Total five year survival rate was 48.9 %. The five year survival rate of operated patients and radiated patients in stageⅠ,Ⅱ were separately 50.1 % and 70.3 % ( P =0.17) without significant statistical differences. Univariate analysis shows tumor stage, size, pathologic type and length of vaginal invasion are prognostic factors( P <0.05),but grade isn't ( P =0.482 7). Multiple regression analysis showed that tumor size ( P =0.013),stage ( P =0.000), length of vaginal invasion were independent prognostic factors.Conclusion:Primary vaginal carcinoma treated by radiation is regarded as first choice. Surgery may be choosed in early stages. Stage, tumor size and length of vaginal invasion are independent prognostic factors.
出处
《肿瘤研究与临床》
CAS
2003年第4期248-250,共3页
Cancer Research and Clinic
关键词
原发性阴道癌
放疗
预后因素
Primary vaginal carcinoma
Radiation
Prognostic factor
