摘要
目的 :总结严重急性呼吸综合征 (SARS)患者的治疗经验。方法 :回顾 2 6例 SARS患者病程的特点和规律 ,分析 X线胸片、血象、血气、电解质、血糖、心肌酶谱及肝肾功能等变化 ,评价西药组 (18例 )和中西药合用组 (8例 )患者药物治疗的效果和无创持续气道正压通气 (CPAP)治疗的意义。结果 :1SARS患者的病程大致分为 4个阶段 :发热初期阶段、肺部渗出进行性加重阶段、严重低氧血症阶段和肺部渗出逐渐吸收阶段。2病毒唑对 SARS病毒无明显效果 ;激素能减轻患者中毒症状 ;病程前期使用中药鱼腥草注射液、清开灵注射液辅助治疗有一定效果。3CPAP能有效提高低氧血症期患者的血氧含量。4中西药组发热、低氧血症持续时间、住院时间和死亡数都较西药组低。结论 :SARS治疗中应合理使用激素和对症支持治疗 ,中药对改善临床症状与预后有益 ;及早发现低氧血症 ,应用
Objective: To summarize the therapeutic experience of severe acute respiratory syndrome(SARS). Methods: The characteristics and kinetic changes of course in 26 patients suffered from SARS were retrospected. The imaging features of pulmonary lesions in chest X-ray radiograms and laboratory's data including hemogram, blood gas, blood glucose, electrolyte, renal function, liver function, and myocardial enzyme were observed. The effects of the medications and noninvasive mechanical ventilation in western medicine(WM) group( n=18 ) and traditional Chinese medicine(TCM) combined WM group( n =8) were evaluated. Results: ①The courses of SARS might be distinguished with early period of fever, inflammatory exudation of lungs, severe hypoxemia and absorption of pulmonary exudative inflammation. ②Ribavirin had no effect on the SARS coronavirus. Glucocorticoid could relieve intoxication of the patients suffered from SARS. The Yuxingcao injection(鱼腥草注射液) and Qingkailing injection(清开灵注射液) had secondary treatment effectiveness in early period. ③The continuous positive airway pressure(CPAP) could increase blood oxygen content for the patients with hypoxemia. ④The continuous time of fever and hypoxemia, the time in hospital and the number of dead patients in TCM combined WM group were all lower than those of the WM group. Conclusion: Appropriate use of glucocorticoid and maintaining treatment for body function should be used in the treatment of SARS. TCM is beneficial to the improvement of clinical symptoms and prognosis and oxygen therapy in time by CPAP should be recommended.
出处
《中国中西医结合急救杂志》
CAS
2003年第4期217-219,共3页
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
