摘要
目的:对比分析用宫颈环形切除术(LEEP)与冷刀锥切术(CKC)治疗子宫颈上皮内瘤变二级(CINII)和子宫颈上皮内瘤变三级(CINIII)的效果。方法 :对2008年1月至2013年12月兖矿集团公司总医院收治的150例CINII和CINIII患者的临床资料进行回顾性分析,将其随机分为LEEP组和CKC组,分别为其采用LEEP与CKC进行手术治疗,并对比分析两组患者的临床疗效。结果 :与CKC组中的CINII及CINIII患者相比,LEEP组中的CINII及CINIIII患者的手术时间均较短,术中的出血量较少,差异显著,有统计学意义(P<0.05)。两组患者在进行手术前后其病灶的病理级别相比较,差异不显著,无统计学意义(P>0.05)。两组患者并发症的发生率相比较,差异不显著(P>0.05),无统计学意义。结论:1采用LEEP与CKC治疗CINII及CINIII的效果无明显的差异性。2在采用LEEP与CKC治疗高级别子宫颈上皮内瘤变时,患者手术并发症的发生率及术后病理分级改变的情况均无显著的差异性,但CINIII患者手术并发症的发生率高于CINII患者。3与采用CKC相比,采用LEEP治疗高级别子宫颈上皮内瘤变具有一定的优越性,如手术的时间较短、无需进行手术麻醉、患者术中的出血量较少、术后住院的天数较短等。
Objective: To compare the clinical effect of LEEP and CKC in the treatment of CINII and CINIII patients, in order to select the optimal treatment. Methods: 150 CINII and CINIII patients in General Hospital of Yankuang Group Company from Jan.2008 to Dec.2013 were selected as the research object. After they were informed and assigned, they were divided into two groups randomly, treated by LEEP or CKC. Their curative effect were compared. Results: The curative effect of two groups were close. The postoperative complications, pathological variation after operation had no significant difference (P>0.05). Patients treated by LEEP had less operation time and bleeding amount than the other patients (P<0.05). Conclusion: The intraoperative and postoperative recovery situation of LEEP show advantages, but CKC still has applicability. Both should complement each other in clinical.
