血清白介素-6 C反应蛋白水平和急性冠状动脉综合征的关系──附30例检测报告被引量：7

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摘要目的:研究急性冠状动脉综合征(acutecoronarysyndrome,ACS)患者血清白介素-6和C反应蛋白水平的变化,为ACS的早期预防及临床干预治疗提供参考。方法:用酶联免疫吸附法测定30例ACS患者和18例稳定型心绞痛(stableanginapectoris,SAP)患者和26名正常人(对照组)的白介素-6、C反应蛋白水平,比较ACS组和SAP组入院时和住院3周后的白介素-6、C反应蛋白水平变化情况。结果:ACS组入院时和住院3周后白介素-6犤(254±70)ng/L,(239±67)ng/L犦、C反应蛋白水平犤(38±18)ng/L,(35±17)ng/L犦分别与SAP组犤(113±41)ng/L、(109±40)ng/L、(4.9±1.8)ng/L、(4.7±2.0)ng/L犦、对照组犤(93±39)ng/L、(3.7±1.5)ng/L犦比较差异均有统计学意义,均为P<0.01,ACS组入院时与住院治疗3周后的白介素-6、C反应蛋白水平比较差异均无统计学意义(均为P>0.05)。而SAP组入院时和住院3周后的白介素-6、C反应蛋白水平与对照组比较差异亦无统计学意义,均为P>0.05。结论:ACS患者血清白介素-6、C反应蛋白水平显著升高,提示炎症反应可能参与了ACS的发生、发展过程,白介素-6、C反应蛋白可作为监测病情的临床生化指标。

作者潘德茂卢健坤郑朝日

机构地区广东徐闻县人民医院内科

出处《新医学》北大核心 2003年第8期493-494,共2页 Journal of New Medicine

关键词急性冠状动脉综合征心肌梗死心绞痛白细胞介素-6 C反应蛋白

分类号 R541.4 [医药卫生—心血管疾病]

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