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加味麻杏石甘汤治疗社区获得性肺炎风温邪热壅肺证临床研究 被引量:9

Clinical Study on Modified Maxing Shigan Tang for Community-acquired Pneumonia with Syndrome of Wind-warm and Evil-heat Accumulated in Lung
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摘要 目的:观察加味麻杏石甘汤治疗社区获得性肺炎风温邪热壅肺证的临床疗效,以期为今后运用中医药治疗社区获得性肺炎提供经验及思路。方法:选取60例社区获得性肺炎风温邪热壅肺证患者,按随机数字表法分为实验组和对照组各30例。对照组给予常规基础治疗,实验组在对照组基础上给予加味麻杏石甘汤口服。观察2组治疗前后的中医证候积分及血白细胞数值(WBC)、血降钙素原(PCT)水平,判定临床疗效。结果:实验组总有效率为93.33%,显著高于对照组的86.67%,差异有统计学意义(P <0.05)。治疗前,2组中医证候积分比较,差异无统计学意义(P> 0.05)。治疗后第1天、第3天、第7天,2组中医证候积分均较治疗前降低,且实验组显著低于同期对照组,差异均有统计学意义(P <0.05)。治疗前,2组血WBC水平比较,差异无统计学意义(P> 0.05)。治疗后第3天、第7天,2组血WBC较治疗前降低,且实验组显著低于同期对照组,差异均有统计学意义(P <0.05)。治疗前,2组血PCT水平比较,差异无统计学意义(P> 0.05)。治疗后第1天、第3天、第7天,2组血PCT较治疗前降低,且实验组显著低于同期对照组,差异均有统计学意义(P <0.05)。结论:加味麻杏石甘汤治疗社区获得性肺炎风温邪热壅肺证的临床疗效较好,值得临床推广应用。 Objective:To observe the clinical effect of modified Maxing Shigan tang for community-acquired pneumonia with syndrome of wind-warm and evil-heat accumulated in lung,in order to provide experience and ideas for the treatment of community-acquired pneumonia with Chinese medicine.Methods:Selected 60 cases of patients with community-acquired pneumonia with syndrome of wind-warm and evil-heat accumulated in lung and divided them into the experiment group and the control group according to the random number table.The control group was given routine basic treatment,while the experiment group was additionally given oral application of modified Maxing Shigan tang.Observed the Chinese medicine syndrome scores and white blood cell(WBC)count and procalcitonin(PCT)levels before and after treatment and evaluated the clinical effect.Results:The total effective rate of the experiment group was 93.33%,being significantly higher than that of86.67%in the control group,difference being significant(P<0.05).Before treatment,there was no significant difference being found in the comparison of the Chinese medicine syndrome scores between the two groups(P>0.05).On the 1 st day,the 3 rd day and the 7 th day after treatment,the Chinese medicine syndrome scores of the two groups were lower than those before the treatment;the score in the experiment group was significantly lower than that in the control group at the same period,differences being significant(P<0.05).Before treatment,there was no significant difference being found in the comparison of the blood WBC levels between the two groups(P>0.05).On the 3 rd and 7 th day after treatment,the blood WBC levels of the two groups were lower than those before treatment;the experiment group was evidently lower than the control group at the same period,differences being significant(P<0.05).Before treatment,there was no significant difference being found in the comparison of the PCT levels between the two groups(P>0.05).On the 1 st day,the 3 rd day and the 7 th day after treatment,the blood PCT levels of the two groups were lower than those before the treatment;the experiment group was obviously lower than the control group,differences being significant(P<0.05).Conclusion:The application of modified Maxing Shigan tang with routine basic treatment has better clinical effect for community-acquired pneumonia,which is worthy of clinical application and promotion.
作者 刘永瑞 于晶 詹少锋 LIU Yongrui;YU Jin;ZHAN Shaofeng
出处 《新中医》 CAS 2019年第8期78-81,共4页 New Chinese Medicine
基金 广东省自然科学基金项目(2017A030310129)
关键词 社区获得性肺炎 风温邪热壅肺证 加味麻杏石甘汤 中医证候积分 血白细胞数值(WBC) 血降钙素原(PCT) Community-acquired pneumonia Syndrome of wind-warm and evil-heat accumulated in lung Modified Maxing Shigan tang Procalcitonin(PCT) White blood cell(WBC) Chinese mediciine syndrome scores
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