摘要
报道了以对羟基苯甲醛为原料,经过硝化、腈化和碘化反应合成牛羊抗肝片吸虫药4-羟基-3-碘-5-硝基苯甲腈的 新方法,总收率为76.9％,纯度达96.8％。
A new method for preparation of 4-hydroxy-3~ iodo-5-nitrobenzonitrile used as a fasciolicide is reported. The title compound was synthesized from p-hydroxyben-zaldehyde by nitration, cyanation and iodination of the product. The total yield reaches 76. 9% and the purity is 96. 8%. The method has a feature of high yield and low cost.
出处
《化学试剂》
CAS
CSCD
北大核心
2003年第4期237-238,240,共3页
Chemical Reagents
