摘要
综述了铬化合物 (Cr)在自然界的存在形式 ,工业用途及其对健康的影响 ,尤其是讨论了铬中间产物Cr(V IV)的形成及其毒性 ,以及它们对DNA损伤的机理 ,进而得出结论 :铬中间产物是造成DNA损伤的主要化合物 。
The existence of chromium complexes in nature, their industrial uses, and their health impacts were reviewed in this paper. The toxic and the formation of Cr(V/IV) complexes and the mechanisms of DNA damage were discussed in particular. The major damaging specises responsible for the genotoxicity were Cr(V) or Cr(IV) complexes. However, the function of reactive organic intermediates could not be excluded.
出处
《卫生研究》
CAS
CSCD
北大核心
2003年第4期410-412,共3页
Journal of Hygiene Research
基金
AustraliaResearchCounciltheUniversityofSydneyCancerResearchFund
