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脊柱单发性浆细胞骨髓瘤的影像学诊断 被引量:12

Imaging diagnosis of solitary plasma myeloma in spine
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摘要 目的 通过对脊柱单发性浆细胞骨髓瘤的影像学表现的分析 ,提高对该疾病的认识。方法 收集 4例脊柱单发性浆细胞骨髓瘤 ,回顾分析其X线平片、CT、MRI表现。结果  3例位于胸椎 ,1例位于腰椎。X线平片显示单个椎体破坏、变形 ;CT显示椎体呈膨胀性破坏 ,病变侵犯一侧附件 ,并在周围形成软组织肿块及压迫硬脊膜囊 ;MRI显示病变椎体呈不均匀信号 ,相邻椎间隙信号不变。 4例尿本 周氏蛋白均为阴性。结论 脊柱SPM依赖影像学检查 :X线平片可作基本定位 ;CT可显示椎体破坏程度及侵犯范围 ;MRI反映病变椎体信号变化、椎间盘结构和椎间隙情况。 Objective\ To analyze imaging findings of solitary plasma myeloma (SPM) in spine and to deepen understanding of the disease .Methods\ 4 cases of SPM in spine were collected.X ray plain films,CT and MRI appearances of SPM were analyzed retrospectively .Results\ 3 cases with thoracic vertebra,and 1 case with lumbar vertebra were found.X ray films revealed destraction and shape change in signal vertebrae body.CT showed expansive osteolytic lesion in vertebrae body.The lesion invaded one appendage and formed a soft tissue mass nearby.MRI showed relatively homogenous isohyperintensity on T\-1WI and hyperintensity on T\-2WI and STIR.Intervertebrae disc were normal.Laboratory studies of all patients showed negative Bence Jones protein in urine.Conclusion\ SPM mainly rely on imaging examination.X ray films may show lesion position,CT may show lesion in size and shape.MRI may show involved vertebra intensity,intervertebrae disc structure and intervertebrae spaces.Final diagnosis needs both myeloid puncture and laboratory examination.
出处 《皖南医学院学报》 CAS 2003年第3期174-177,共4页 Journal of Wannan Medical College
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参考文献7

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二级参考文献5

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