摘要
目的 :探讨米诺环素对慢性牙周炎的辅助治疗作用。方法 :将 2 0个病例中患中度及重度慢性牙周炎的患牙 80个随机分成 4组 :①米诺环素 +刮治组 (SRP +M ) ;②单纯刮治组 (SRP) ;③单纯用米诺环素组 (M ) ;④未处理组 (U)。分别在基线、1周 ,4周时检测菌斑指数 (PI)、牙龈指数 (GI)、探诊出血指数 (BOP)、探诊深度 (PD)、附着丧失 (AL)等牙周病临床指标。结果 :SRP +M组在 1周和 4周时探诊深度和探诊出血率显著低于其它 3组 (P <0 .0 5 )。结论 :龈下局部应用米诺环素联合刮治术和根面平整术在降低探诊深度和探诊出血方面比单纯实施刮治术和根面平整术组效果明显。
Objective: To evaluate the adjunctive benefits of minocycline in the treatment of chronic periodontitis .Method: 4 teeth in 20 patients with moderate to advanced periodontitis were randomly divided into four groups: ①minocycline plus scaling and root planning(SRP+M) ②scaling and root planning alone(SRP) ③minocycline alone(M) ④untreated group(U). All parameters including plaque index(PI),gingival index(GI),bleeding on probing(BOP),probing depth(PD) and attachment loss(AL) were measured at baseline,1 and 4 weeks after treatment. Result: SRP+M resulted in a significant reduction in PD and in BOP rate compared to the other three groups(P<0.05).Conclusion: Subgingival minocycline plus scaling and root planning resulted in more PD and BOP reduction than scaling and root planning alone, therefore, minocycline plus SRP can be effectively used in the treatment of chronic periodontitis.
出处
《临床口腔医学杂志》
2003年第9期542-544,共3页
Journal of Clinical Stomatology
关键词
米诺环素
慢性牙周炎
辅助治疗
作用
根面平整术
minocycline/therapeutic use
periodontal diseases/drug therapy
scaling
root planning
