急性肝衰竭并发肝性脑病患者血清甲状腺激素水平变化被引量：2

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摘要目的检测急性肝衰竭并发肝性脑病(HE)患者血清甲状腺激素水平,探讨甲状腺激素水平变化与HE分级的关系。方法选择急性肝衰竭并发HE患者72例(观察组)和急性重症肝炎患者76例(对照组)。采用化学发光法检测两组血清总甲状腺素(TT4)、总三碘甲状腺原氨酸(TT3)、游离甲状腺素(FT4)、游离三碘甲状腺原氨酸(FT3)、促甲状腺素(TSH),采用Spearman相关分析HE分级与血清甲状腺激素的关系。结果观察组血清TSH低于对照组,FT4高于对照组,P均<0.05;两组血清TT4、TT3、FT3比较,P均>0.05。观察组中,HE分级2、3、4级患者血清TSH依次降低,P均<0.05;HE分级与血清TSH呈负相关(r=-0.661,P<0.001),与血清FT4无关(r=0.089,P>0.05)。结论急性肝衰竭并发HE患者血清TSH降低,并与HE病情有关。

作者张贵贤于万友曹武奎袁桂玉李谦

机构地区天津市第二人民医院

出处《山东医药》 CAS 北大核心 2015年第20期76-77,共2页 Shandong Medical Journal

关键词急性肝衰竭肝性脑病甲状腺激素

分类号 R575.3 [医药卫生—消化系统]

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