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红鹿合剂联合癃清胶囊治疗湿热瘀阻型慢性非细菌性前列腺炎的临床研究 被引量:13

Clinical research on Honglu Mixture combine with Longqing Capsule in the treatment of chronic nonbacterial prostatitis with syndrome of stagnant dampness-heat
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摘要 目的观察红鹿合剂联合癃清胶囊治疗湿热瘀阻型慢性非细菌性前列腺炎的临床效果。方法将84例湿热瘀阻型慢性非细菌性前列腺炎患者随机分为治疗组与对照组,每组42例。治疗组予红鹿合剂联合癃清胶囊,对照组予盐酸坦洛新缓释胶囊。两组疗程均为1个月,观察临床疗效,比较NIH-CPSI评分及前列腺液常规指标的变化情况。结果(1)治疗组、对照组临床总有效率分别为92.96%和69.01%;组间临床疗效比较,治疗组明显优于对照组(P<0.05)。(2)治疗前后组内比较,两组疼痛、排尿、生活质量评分及CPSI总评分差异均有统计学意义(P<0.05);组间治疗后比较,疼痛评分及CPSI总评分差异有统计学意义(P<0.05)。(3)治疗前后组内比较,两组白细胞(WBC)、卵磷脂小体(SPL)水平差异均有统计学意义(P<0.05);组间治疗后比较,治疗组WBC、SPL水平改善程度明显优于对照组(P<0.05)。结论红鹿合剂联合癃清胶囊治疗湿热瘀阻型慢性非细菌性前列腺炎,可明显缓解患者疼痛、尿频、尿急等症状,改善其前列腺功能。 Objective To observe the clinical efficacy of Honglu Mixture combined with Longqing Capsule in the treatment of chronic nonbacterial prostatitis with syndrome of stagnant dampness-heat.Methods 84 cases of chronic nonbacterial prostatitis with syndrome of stagnant dampness-heat were randomly divided into the treatment group and the control group,42 patients in each group.The treatment group was treated with Honglu Mixture combine with Longqing Capsule,while the control group was treated with tamsulosin hydrochloride sustained-release capsule,with a course of one month.The clinical efficacy was observed,the changes of National Institutes of Health Chronic Prostatitis Symptom Index(NIH-CPSI)and routine indexes of prostatic fluid were compared.Results(1)The total effective rate was 92.96% in the treatment group and 69.01% in the control group.The clinical efficacy of the treatment group was significantly better than that of the control group(P<0.05).(2)For the comparison of treatment before and after within group,there were statistically significant differences on the scores of pain,urination and life quality and the total score of CPSI in both groups(P<0.05);for the comparison between the two groups after treatment,there were statistically significant differences on the score of pain and the total score of CPSI(P<0.05).(3)For the comparison of treatment before and after within group,there were statistically significant differences on the levels of white blood cell(WBC)and small particle of lecithin(SPL)in both groups(P<0.05);for the comparison between the two groups after treatment,the improvement on the levels of WBC and SPL in the treatment group was significantly better than that of the control group(P<0.05).ConclusionHonglu Mixture combined with Longqing Capsule can be used in the treatment of chronic nonbacterial prostatitis with syndrome of stagnant dampness-heat,which significantly relieve the symptoms such as pain,frequent urination,urgent urination,and improve the function of the prostate.
出处 《上海中医药杂志》 2017年第3期57-60,共4页 Shanghai Journal of Traditional Chinese Medicine
基金 上海市卫生局中西医结合前列腺癌特色专科建设项目(ZXBZ2012-07)
关键词 慢性非细菌性前列腺炎 红鹿合剂 癃清胶囊 湿热 血瘀 微循环 chronic nonbacterial prostatitis Honglu Mixture Longqing Capsule dampness-heat blood stasis microcirculation
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