Synthesis and Photocleaving DNA Activity of 4′-Chlorobenzene-sulfonyl Chloride-pyrrolecarboxamide Hybrid Compound

Synthesis and Photocleaving DNA Activity of 4′-Chlorobenzene-sulfonyl Chloride-pyrrolecarboxamide Hybrid Compound

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摘要 A 4′-chlorobenzenesulfonyl chloride-pyrrolecarboxamide hybrid compound was synthesized and its DNA cleaving activity was investigated using a pBluescript SK DNA under UV irradiation. This compound showed potent DNA cleaving activity. A 4′-chlorobenzenesulfonyl chloride-pyrrolecarboxamide hybrid compound was synthesized and its DNA cleaving activity was investigated using a pBluescript SK DNA under UV irradiation. This compound showed potent DNA cleaving activity.

作者汤菲力袁谷

机构地区 Laboratory of Bioorganic Chemistry and Molecular Engineering

出处《Chinese Journal of Chemistry》 SCIE CAS CSCD 2003年第9期1238-1240,共3页 中国化学（英文版）

基金 theNationalNaturalScienceFoundationofChina (Nos .39970 16 9and 2 9872 0 0 1)

关键词 photonuclease DNA cleaving POLYAMIDE photonuclease, DNA cleaving, polyamide

分类号 O621 [理学—有机化学]

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1Blasko A,Browne K A,Bruice T C. J. Journal of the American Chemical Society . 1994
2S. M. Touami,C. C. Poon,P. A. Wender.Sequence Specific DNA Cleavage by Conjugates of Benzotriazoles and Minor Groove Binders[].Journal of the American Chemical Society.1997
3Xiao,J.H,Yuan,G.,Huang,W.Q.,Chan,A.S.C.,Lee,K.L.D. Journal of Organic Chemistry . 2000
4Tang,F.,Wang,J.,Liu,D.,Li,J.,Yuan,G.Systematical synthesis of distamycin analogues and their interaction with herring sperm DNA[].J Chin Chem Soc-Taip.2002
5ArmitageB. Chemical Reviews . 1998
6Ros,T .D,Spalluto,G,Boutorine,A .S,Bensasson,R .V,Prato,M. Curr.Pharm.Des . 2001
7Mastumoto,T,Sakai,Y,Toyooka,K,Shibuya,M. Hete rocycles . 1992
8Tang,F .L,Wang,J,Liu,D,Yuan,G,Liu,Y,Zhu,C .J,Zhao,Y .F. RapidCommun.MassSpectrom . 2002

1Jun Lu,Hai Yang Liu,Lei Shi,Xiang Li Wang,Xiao Ying,Lei Zhang,Liang Nian Ji,Lin Quan Zang,Chi K. Chang.DNA cleavage mediated by water-soluble manganese corrole[J].Chinese Chemical Letters,2011,22(1):101-104. 被引量：7
2Feng LIN,Jin Long WU,Xiao Wei FAN (Department of Chemistry, Zhejiang University. Hangzhou 310028).A Novel Photoproduct of 2-Methoxycytosine in Phosphate Solution Under Far UV Irradiation[J].Chinese Chemical Letters,1999,10(8):623-624.
3HUANG Yingping,LIU Xiangling,FANG Yanfen,WANG Qi,LAU Kingtong.Degradation of 2, 4-D Acid Using Mn～(2+) as Catalyst under UV Irradiation[J].Wuhan University Journal of Natural Sciences,2009,14(3):262-266.
4汤新之.细胞凋亡的生物化学(一)──DNA裂解和信号传递系统[J].中国中西医结合外科杂志,1997,3(6):414-418.
5宗良,董俊军,陈静,李建,隋少卉,魏一飞,张鸣.用于肽合成的肟铯盐裂解剂的制备及性能[J].高等学校化学学报,2016,37(7):1328-1334. 被引量：2
6吴玮,孔宪涛,李雨,杨如俊,屈昌民,李莉,张玲珍.^(60)Coγ射线诱发小鼠胸腺细胞凋亡及其DNA裂解测定方法的研究[J].中华放射医学与防护杂志,1998,18(3):169-170. 被引量：3
7王心葵,解红娟,程爱华,彭少逸.丙烷在磷改性的HZSM-5上的芳构化反应[J].燃料化学学报,1991,19(4):298-303. 被引量：3
8SHEN Yue YU Li NIU Jing-Yang WANG Jing-Ping.Hydrothermal Synthesis and Crystal Structure of a Hybrid Compound Based on β-Octamolybdate [Mn(2,2’-bipy)_3]_2[β-Mo_8O_(26)]·4H_2O[J].Chinese Journal of Structural Chemistry,2005,24(10):1164-1168. 被引量：1
9Philippe Horvath,Rodolphe Barrangou.RNA-guided genome editing a la carte[J].Cell Research,2013,23(6):733-734. 被引量：3
10张立康,张正.相转移催化下4-氯苯磺酰基乙酸异丙酯的烷基化反应[J].高等学校化学学报,1991,12(4):491-493.

Chinese Journal of Chemistry

2003年第9期

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Synthesis and Photocleaving DNA Activity of 4′-Chlorobenzene-sulfonyl Chloride-pyrrolecarboxamide Hybrid Compound

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