摘要
目的比较不同方式宫颈广泛性切除术治疗早期子宫颈癌年轻患者的临床疗效。方法选择203例早期子宫颈癌年轻患者为研究对象,根据手术方式的不同将患者分为A组与B组,A组患者行阴式宫颈广泛性切除术加腹腔镜盆腔淋巴结清扫术,B组患者接受开腹宫颈广泛性切除术加盆腔淋巴结清扫术。比较2组手术效果、术后并发症发生率及复发情况。结果 A组阴道切除长度及术中出血量均显著少于B组(P<0.05);A组术后肛管排气时间、肠鸣音恢复时间显著早于B组(P<0.05);2组淋巴结清除数目、手术时间及宫颈切除长度均未见显著差异(P>0.05);A组妊娠率、复发率及并发症发生率分别为33.7%、7.9%和13.9%,B组分别为31.4%、6.9%和16.7%,差异无统计学意义(P>0.05)。结论阴式宫颈广泛性切除术加腹腔镜盆腔淋巴结清扫术治疗早期子宫颈癌年轻患者安全可行,可减少手术损伤,并促进术后胃肠功能恢复。
Objective To compare the clinical efficacy of different radical trachelectomy in young patients with early stage cervical carcinoma .Methods 203 young patients with early stage cervical carcinoma were divided into group A and group B according to operational manner .Group A received vaginal radical trachelectomy and pelvic lymph node dissection ,and group B were given abdominal radical trachelectomy and pelvic lymph node dissection .Operation effect,operation time,adverse reaction rate and recurrence were compared between the 2 groups.Results The length of vaginal hysterectomy and intraoperative blood loss of group A were much lower than those of group B (P<0.05),and postoperative anal exhaust time and time needed for in-testinal voice restoration in group A was shorter than that of group B (P<0.05);There were no significant difference in the num-ber of dissected lymph nodes ,operation time and the height of the cervical resection between the 2 groups (P>0.05);Pregnancy rate,recurrence rate and adverse reaction rate in group A were 33.7%,7.9% and 13.9%,and 31.4%,6.9% and 16.7% in group B,respectively,there had no significant difference (P >0.05).Conclusion Vaginal radical trachelectomy and pelvic lymph node dissection for early stage cervical carcinoma are safe and feasible ,and can decrease operative injury and promote re-covery of digestive function .
出处
《实用癌症杂志》
2014年第7期838-840,共3页
The Practical Journal of Cancer
关键词
宫颈肿瘤
根治性子宫颈切除术
保留生育能力
Uterine cervical neoplasms
Radical trachelectomy
Fertility preservation
