摘要
目的探讨CT引导下经皮肺穿刺活检对早期诊断肺癌的临床应用价值,并与超声进行对比。方法回顾分析1940例疑似肺癌活检患者临床资料,按获取活检组织方法不同分为2组,970例行CT引导下经皮肺穿刺活检(CT组),另970例行超声引导下经皮肺穿刺活检(超声组)。以手术获取的病理组织活检为标准,对比2组特异度、敏感度、误诊率、漏诊率、并发症发生率。分析CT诊断在不同年龄、病灶大小、穿刺深度患者的敏感度。结果 CT组特异度(91. 19%)、敏感度(97. 75%)、误诊率(8. 81%)、漏诊率(2. 05%)与超声组特异度(86. 13%)、敏感度(92. 44%)、误诊率(13. 87%)、漏诊率(7. 56%)比较,差异无统计学意义(P>0. 05)。CT组并发症发生率(12. 89%)与超声组(13. 30%)比较,差异无统计学意义(P>0. 05)。CT引导下经皮肺穿刺活检诊断肺癌的敏感度与年龄、病灶大小、穿刺深度无关。结论 CT引导下经皮肺穿刺活检诊断肺癌特异性、敏感度高,误诊率、漏诊率、并发症发生率低,其价值与超声相当,且不受穿刺深度、病灶大小及年龄影响,但需要积极预防气胸和出血。
Objective To analyze the clinical value of CT-guided percutaneous lung biopsy in the early diagnosis of lung cancer and to compare with ultrasound.Methods The clinical data of 1940 suspected lung cancer biopsy patients from January2011 to June 2017 were retrospectively analyzed.According to the biopsy method,the patients were divided into two groups,970 patients underwent CT guided percutaneous lung biopsy(CT group),and the other 970 Routine ultrasound guided percutaneous lung biopsy(ultrasound group).Finally,the pathological biopsy obtained by surgery as the standard,and the two groups of specificity,sensitivity,misdiagnosis rate,missed diagnosis rate and complication rate was compared.The diagnostic sensitivity of CT patients at different age,lesion size,and depth of penetration was analyzed.Results The specificity of CT group was 91.19%,the sensitivity was 97.75%,the rate of misdiagnosis was 8.81%,the rate of missed diagnosis was 2.05%,and the specificity of ultrasound group was 86.13%,the sensitivity was 92.44%,the rate of misdiagnosis was 13.87%,the rate of missed diagnosis was7.56%,compare them between the two group,the difference was not statistically significant(P>0.05).There was no significant difference in CT group incidence(12.89%)vs ultrasound group(13.30%)(P>0.05).The sensitivity of CT guided percutaneous lung biopsy in the diagnosis of lung cancer has nothing to do with the age,the size of the lesion and the depth of the puncture.Conclusion CT-guided percutaneous lung biopsy can diagnose lung cancer with high specificity,high sensitivity,low misdiagnosis rate,missed diagnosis rate and low complication rate.Its value is comparable with that of ultrasound,and it is not influenced by depth of lesion,size of lesion and age,But it need to actively prevent pneumothorax and bleeding.
作者
李雪
张申众
袁秀敏
门桐林
张璐
王艳
LI Xue;ZHANG Shenzhong;YUAN Xiumin(The Tenth People's Hospital of Shenyang City,Shenyang,110044)
出处
《实用癌症杂志》
2019年第4期603-606,共4页
The Practical Journal of Cancer
