摘要
目的探讨两种手术方式对T2～T3肌层浸润性膀胱癌患者的术后生活质量和远期疗效的影响。方法选取T2～T3肌层浸润性膀胱癌患者61例进行回顾性分析,按照手术方式不同分为两组,A组采用膀胱部分切除术,共31例,B组采用根治性膀胱切除术,共30例。比较两组患者的术后生活质量及不同分期的远期生存率。结果 A组患者生活质量各维度评分均显著高于B组(P <0. 05); B组中T2期患者的1年生存率、3年生存率和5年生存率与A组相比无显著性差异(P>0. 05); B组中T3期患者的1年生存率和3年生存率与A组相比无显著性差异(P>0. 05),但B组的5年生存率显著高于A组(P <0. 05); B组所有患者1年生存率与A组相比无统计学差异(P> 0. 05),但3年生存率和5年生存率均显著高于A组(P <0. 05)。结论部分膀胱切除术患者的术后生活质量明显优于根治性膀胱切除术,但对于T3期患者根治性膀胱切除术的5年生存率较高,而对于T2期患者两种手术方式的远期生存率无显著性差异,可为临床手术方式的选择提供参考。
Objective To explore the effect of two surgical methods on postoperative quality of life and long-term effect of patients with infiltrating bladder cancer(T2~T3).Methods 61 patients with invasive bladder cancer(T2~T3)were selected in our hospital,and divided into two groups according to the operation way.Total of 31 patients underwent partial cystectomy in group A,and total of 30 patients underwent radical cystectomy in group B.The postoperative quality of life and the long-term survival rate of different stages were compared between the two groups.Results The quality of life of patients in group A was significantly higher than that in group B(P<0.05).The 1-year survival rate,3-year survival rate and 5-year survival rate of T2 patients in group B had no significant difference compared with group A(P>0.05).The 1-year survival rate and 3-year survival rate of T3 patients in group B had no significant difference compared with group A(P>0.05),but the 5-year survival rate in group B was significantly higher than that in group A(P<0.05).The 1-year survival rate of all patients in group B was not statistically significant compared with group A(P>0.05),but the 3 years survival rate and 5-year survival rate were significantly higher than that of group A(P<0.05).Conclusion The postoperative life quality of patients with partial cystectomy was significantly better than that of radical cystectomy.But for the 5-year survival rate of patients with T3 radical cystectomy is higher,while for T2 two operation methods with no significant differences,can provide reference for the choice of the ways of clinical surgery.
作者
周俊
陈如
马锋
ZHOU Jun;CHEN Ru;MA Feng(San Er Ling Yi Affiliated Hospital of XI’AN Jiaotong University,Hanzhong,723000)
出处
《实用癌症杂志》
2019年第4期672-674,共3页
The Practical Journal of Cancer
关键词
手术方式
T2~T3肌层浸润性膀胱癌
远期生存率
Two surgical methods
Intramuscular invasive bladder cancer(T2~T3)
Long-term survival rate
