摘要
目的探讨尿毒症患者维持性血液透析(MHD)动脉粥样硬化及其危险因素的研究。方法选择在血透室治疗的 MHD 患者30例,健康体检者21名为对照组,进行颈动脉高频彩色多普勒超声检查,测量血清 C 反应蛋白(CRP),肿瘤坏死因子(TNF)a,血糖(GIU),白蛋白(ALB)浓度及钙磷乘积,对病例组及对照组诸指标进行分析。结果病例组与对照组比较,颈动脉内膜-中层厚度(IMT),CRP,TNFa 钙磷乘积(Ca×P)均明显增高,ALB 则明显降低,GIU 两者差异无显著性。结论尿毒症血液透析患者颈动脉硬化与炎症的营养不良状态具有相关性,后者是前者的危险因素。
Objective To evaluate the atherosclerotic and its risk factors in uremia patients with treated with hemodialy- sis.Methods the 30 cases of MHD patients and 21 health controls were chosen,the colour doppler's examination in neck atreria,serum CRP,,TNF-α,serum glucose,albumin and the calcium times phorphorus were analysed.Re- sults the IMT index,the level of CRP,TNF-αand Ca * P were higher in patients group than those of in control group,the level of albumin in patients group was decreased significantly and the level of Glu was not difference.Con- clusion the arteriosclerosis in uremia patients is related to the infections and nutrition status,the later is the risk factor of the former.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2006年第S2期10-11,共2页
Chinese Journal of Practical Internal Medicine
基金
汕头市重点科技计划项目(0682)
