摘要
药物诱导的自身免疫性肝炎(drug induced autoimmune hepatitis,DIAIH)是由药物触发自身免疫系统导致的肝损伤,近年来临床报道明显增多。DIAIH的临床特征不典型,发病机制尚未完全阐明,亦无特异性的诊断标准,临床诊断困难,治疗和预后仍存在争议。文章对DIAIH的临床特点和治疗进行了阐述,以期提高临床医生对DIAIH的认识及诊治水平。
Drug-induced autoimmune hepatitis(DIAIH)refers to liver injury mediated by the autoimmune system activated by drugs.The clinical reports of DIAIH have increased significantly in recent years.The clinical features of DIAIH are non-typical,the pathogenesis remains unclear,and there are no specific diagnostic criteria,which causes the difficulties in clinical diagnosis,and treatment and prognosis remain controversial.This paper will make a review about clinical features and treatment of DIAIH,in order to help clinicians learn more about DIAIH and improve the clinical diagnosis and treatment.
作者
姚岚
丁洋
YAO Lan;DING Yang(Infectious Disease Department,Shengjing Hospital of China Medical University,Shenyang 110022,China)
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2019年第6期498-500,共3页
Chinese Journal of Practical Internal Medicine
关键词
药物
自身免疫性肝炎
临床特点
治疗
drug
autoimmune hepatitis
clinical characteristics
treatment
