摘要
目的观察卤米松乳膏和丙酸氯倍他索乳膏治疗湿疹患者的起效时间和临床疗效。方法按随机分配原则将61例湿疹患者分成两组,分别用0.05%卤米松乳膏和0.02%丙酸氯倍他索乳膏外涂皮损处,疗程14 d。在治疗第0、1、3、5、10、14天对患者进行随访。结果卤米松组患者治疗有效率与丙酸氯倍他索组患者相比,无明显差别,两种药物均对湿疹患者具有良好疗效,但卤米松组患者的药物平均起效时间为(8.9±3.6)d,丙酸氯倍他索组患者为(11.3±2.2)d,组间差异有统计学意义(P=0.026)。结论卤米松乳膏和丙酸氯倍他索乳膏治疗湿疹总体疗效相当,但卤米松乳膏起效较快。
Objective To evaluate the onset time and clinical effects of halometasone cream and clobetasol propionate cream on patients with eczema.Methods A total of 61 patients with eczema were randomly divided into two groups to conduct random comparison research.The patients were treated with 0.05%halometasone cream in the study group or with 0.02%clobetasol propionate cream in the control group for 2 weeks.Patient assessments were conducted at 6 time nodes(enrollment,1 st,3 rd,5 th,10 th and 14 th day of treatment).Results There was no significant difference between the study group and the control group on the efficiency.The onset time of study group(8.9±3.6)d was shorter than that of the control group(11.3±2.2)d.Conclusion Halometasone cream and clobetasol propionate cream have the same overall efficacy in the treatment of eczema,but halometasone cream onset more faster.
作者
黄敏
张钧芬
王文娟
赵梓纲
林碧雯
郝甜
杨怡
李承新
HUANG Min;ZHANG Jun-fen;WANG Wen-juan(Department of Dermatology,Chinese PLA General Hospital&Medical School of Chinse PLA(301 Hospital),Beijing 100853,China)
出处
《实用皮肤病学杂志》
2019年第4期197-200,共4页
Journal of Practical Dermatology
基金
国家自然基金面上资助项目(81572680)
关键词
湿疹
卤米松
丙酸氯倍他索
起效时间
Eczema
Halometasone
Clobetasol propionate
Onset time
