摘要
早期复极综合征的发现已经70多年,长期以来它一直被认为是良性心电图变异而未引起足够重视,直到2008年报道早期复极综合征与恶性心律失常致心源性猝死相关,才引起人们的关注。如何筛查出猝死高危患者是当前研究的热点。从基因组学到离子通道、J波形态,均可提供早期复极综合征危险分层的信息,综合运用效果可能更好。目前对于早期复极综合征的治疗仅限于二级预防,射频消融、ICD植入可能挽救患者生命。
It is over 70 years since early repolarization syndrome( ERS) was found for the first time. It has long been regarded as benign electrocardiographic variation and has never aroused enough attention until the relationship between ERS and malignant arrhythmia-induced sudden cardiac death was reported in 2008. How to screen the patients at high risk of sudden death is the hotspot of research. The information of ERS risk stratification can be provided by Genomics,ion channels,and J-wave morphology,an integrated application of which may work better. At present,ERS treatment is limited to secondary prevention,and radiofrequency ablation and ICD implantation may save the lives of patients.
出处
《江苏实用心电学杂志》
2015年第1期1-8,共8页
Journal of Practical Electrocardiology JS
基金
河北省卫生厅重点课题计划项目(20120170)
关键词
早期复极综合征
危险分层
心源性猝死
J波形态
early repolarization syndrome
risk stratification
sudden cardiac death
J-wave morphology
