摘要
目的分析胃镜下注射去甲肾上腺素及静注泮托拉唑联合金属钛夹治疗消化性溃疡并出血的疗效。方法回顾性分析湖北省武汉市新洲区人民医院给予胃镜下注射去甲肾上腺素+静注泮托拉唑治疗(对照组)及静注泮托拉唑+胃镜下注射去甲肾上腺素+金属钛夹治疗(观察组)的消化性溃疡并出血患者各63例临床资料。记录两组止血效果、治疗7 d内呕血、黑便发生次数及住院时间、不良反应发生情况,并比较治疗前及治疗3 d后脉搏、休克指数(SI)差异。结果观察组12 h内止血率及48 h内止血率明显高于对照组(P<0.05),而48 h后活动性出血率、治疗7 d内呕血、黑便发生次数及住院时间均低于对照组(P<0.05)。两组不良反应发生情况比较,差异无统计学意义(P<0.05)。治疗3 d后,两组脉搏、SI均较治疗前降低(P<0.05),且观察组低于对照组(P<0.05)。结论静注泮托拉唑+胃镜下注射去甲肾上腺素+金属钛夹治疗消化性溃疡并出血效果更佳,不仅能尽快止血,且不良反应较少,于促进患者生命体征平稳也有利。
Objective To analyze the efficacy of gastroscopic injection of norepinephrine and intravenous injection of pantoprazole combined with metal titanic clip in the treatment of peptic ulcer bleeding.Methods A retrospective analysis was performed on clinical data of each 63 patients with peptic ulcer bleeding who were given gastroscopic injection of norepinephrine+intravenous injection of pantoprazole(control group)or given intravenous injection of pantoprazole+gastroscopic injection of norepinephrine+metal titanic clip(observation group)in hospital.The hemostatic effects,frequencies of haematemesis and melena within 7 d of treatment,hospital stay and occurrence of adverse reactions were recorded in the two groups,and the in pulse and shock index(SI)were compared before treatment and after 3 d of treatment.Results The hemostasis rate within 12 h and hemostasis rate within 48 h in observation group were significantly higher than those in control group(P<0.05)while the active bleeding rate after 48 h,frequencies of haematemesis and melena within 7 d of treatment and hospital stay were lower than those in control group(P<0.05).There was no significant difference in the occurrence of adverse reactions between the two groups(P<0.05).After 3 d of treatment,the pulse and SI in the two groups were decreased compared with those before treatment(P<0.05),and the two indexes in observation group were lower than those in control group(P<0.05).Conclusion Intravenous injection of pantoprazole+gastroscopic injection of norepinephrine+metal titanic clip has better effects in the treatment of peptic ulcer bleeding,and it can not only stop bleeding as soon as possible,and it has fewer adverse reactions,and it is also beneficial to promote the stability of vital signs.
作者
罗正武
李丽平
LUO Zhengwu;LI Liping(Wuhan Xinzhou District People's Hospital,Wuhan 431400,China)
出处
《实用心脑肺血管病杂志》
2019年第S1期59-61,共3页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
