摘要
目的:探讨乳头状肾细胞癌的螺旋CT征象与病理之间的关系。方法:回顾性分析10例经手术病理证实的乳头状肾细胞癌术前的螺旋CT征象及手术病理结果进行对照分析。结果:CT主要特点为:增强扫描肿瘤呈较均匀或不均匀轻中度强化;肾周间隙受侵征象有结节、条索状影、棘状突起和肾周筋膜增厚。MVD及VEGF表达与肾癌分期、肿瘤强化程度有相关性(P<0.05),与肿瘤密度、最大径及肾周间隙受侵征象无相关性(P>0.05)。结论:螺旋CT较好显示乳头状肾癌的影像特征,与肾透明细胞癌有明显不同,有助于鉴别诊断;并可推断PRCC中MVD、VEGF的表达,在一定程度上可无创地从分子水平判断PRCC的发生、发展、侵袭和转移情况。
Objective To analyze the relationship between spiral CT signs and pathology in PRCC.Methods 10 patients with pathologically proved PRCC were retrospectively analyzed.All patients were examined with spiral CT in plain and multiphase enhancement scans before operation.CT features of PRCC were compared with surgical and pathological results.Results The enhancement features of PRCC on contrast CT was homogeneous or inhomogeneous enhancement,and was light to moderate strengthening.CT features of perinephric space abnormalities included nodus,trabs,spine-like process and thickening of the perirenal fascia.The enhancement degree of PRCC on contrast CT and staging of PRCC was closely correlated to the MVD and VEGF of PRCC(P<0.05).There were not correlation between the density,diameter,features of perinephric space abnormalities of PRCC and MVD,so the VEGF(P>0.05).Conclusion Spiral CT could distinctly show imaging characteristics of PRCC,which is different the characteristics of CRCC.The MVD and expression of VEGF could be deduced according to the SCT features of PRCC,so that multiphasic SCT enhanced scans may be a noninvasive method to predict production,aggressiveness and prognosis of PRCC at molecular biological level.
出处
《实用医技杂志》
2008年第6期710-712,共3页
Journal of Practical Medical Techniques
关键词
乳头状肾细胞癌
体层摄影
X线计算机
病理
Papillary renal cell carcinoma
Tomography
X-ray computer
Pathology
