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喜炎平雾化吸入联合利巴韦林治疗小儿疱疹性咽峡炎随机平行对照研究 被引量:5

Xi Phlogistic Flat Atomized Inhalation Plus Ribavirin in the Treatment of Infantile Herpangina Random Parallel Control Study
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摘要 [目的]观察喜炎平雾化吸入联合利巴韦林治疗小儿疱疹性咽峡炎疗效。[方法]使用随机平行对照方法,将60例住院患者按就诊顺序编号随机分为两组。对照组30例干扰素10万U加入生理盐水10mL雾化吸入,2次/d。治疗组30例喜炎平,5mg/Kg加入生理盐水10mL雾化吸入,2次/d。利巴韦林气雾剂(信韦林)间歇2h喷射咽喉及软腭1次。连续治疗5d为1疗程。观测临床症状、退热时间、疱疹消失时间、不良反应。治疗1疗程,判定疗效。[结果]治疗组显效14例,有效14例,无效2例,总有效率93.33%。对照组显效8例,有效15例,无效7例,总有效率76.67%。治疗组疗效优于对照组(P<0.05)。时间指标治疗组优于对照组(P<0.05)。[结论]喜炎平雾化吸入联合利巴韦林治疗小儿疱疹性咽峡炎可缩短病程,值得推广。 [Objective]To observe the xi phlogistic flat atomized inhalation plus ribavirin in the treatment of infantile herpangina curative effect.[Methods]Using random parallel control method,60 cases of hospitalized patients in clinic order Numbers randomly divided into two groups. 100000 units to join saline control group 30 cases interferon 10 ml aerosol inhalation,2 times/d. Treatment group 30 cases of xi ping,5 mg/Kg to join saline 10 ml aerosol inhalation,2 times/d. Waring ribavirin aerosol(letter)intermittent 2 h 1 injection throat and the soft palate. Continuous treatment 5 d to 1 course of treatment. Observation of clinical symptoms,antifebrile time disappear,herpes,adverse reactions. Continuous treatment 1 treatment course,judge curative effect.[Results]The treatment group 14 cases had marked effect,14 cases effective,ineffective in 2 cases,total effective rate was 93.33%.The control group,8 cases were markedly improved effective 15 cases,7 cases,total effective rate was 76.67%. The treatment group curative effect is better than that of control group(P<0.05). Timing indicators in treatment group is better than that of control group(P<0.05).[Conclusion]Xi phlogistic flat atomized inhalation plus ribavirin in the treatment of infantile herpangina can shorten the course of the disease,is worth promoting.
作者 张静
出处 《实用中医内科杂志》 2013年第6S期109-110,共2页 Journal of Practical Traditional Chinese Internal Medicine
关键词 小儿疱疹性咽峡炎 喜炎平 雾化 利巴韦林 随机平行对照研究 Infantile herpangina Xi phlogistic flat Atomization Ribavirin Random parallel control study
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