摘要
目的 :探讨活动性指数 (AI)与慢性指数 (CI)对狼疮性肾炎 (LN)治疗的指导意义。方法 :对 4 8例LN患者的肾活检标本予半定量法评分 ,并对不同分值AI、CI的治疗方法、疗效进行对比分析。结果 :AI≥ 1 0组与AI <1 0组疗效无显著差异 (P>0 0 5 ) ,对AI≥ 1 0组予强化治疗 ,可大大提高缓解率 ;CI≥ 6组与CI<6组疗效有非常显著性差异 (P <0 0 1 )。结论 :AI值越高 ,应予积极治疗 ,AI≥ 1 0 ,强化治疗可改善预后。CI值越高 。
Objective:To inrestigate the clinical significance of activity index(AI) and chronic index(CI) in the treatment of patients with lupus nephtitis(LN).Methods:48 patients with LN were included in this study.Their renal tissue slices were evaluated by semiquantitative analysis,and the score of AI and CI was obtained.The therapeutic method and efficiency of the patients with lifferent AI or CI were compared.Result:There was no significance in therapeutic efficiency between the group of AI≥10 and the group of AI<10(P>0 05).When the patients in group of AI≥10 were potentiated,their remission rate was improved greatly.There was significance in therapeutic efficiency between the group of CI≥6 and the group of CI<6(P<0 01).Conclusion:The patients with high score of AI should be treated actively.The prognosis of the patients with AI≥10 is improved by potentated thearapy.The higher score of CI,the worse therapeutic efficiency.
出处
《广西医学》
CAS
2003年第9期1597-1598,共2页
Guangxi Medical Journal
关键词
狼疮性肾炎
活动性指数
慢性指数
治疗
Lupus nephritis
Activity index
Chronicity index
Treatment
