摘要
人干细胞是具有自我复制和分化潜能的细胞 ,有很多种类 ,在人体发育中起着决定性的作用。干细胞的分化是干细胞研究的核心内容 ,除了受干细胞自身分化潜能制约外 ,同时受干细胞周围环境的控制。人干细胞的分化研究分为体外研究和体内研究 ,除观察人干细胞诱导分化后的形态变化外 ,同时也探索细胞分化的分子机制。人们关注人干细胞的研究 ,目的就是体外扩增干细胞并获得具有定向分化能力的干细胞 ,采用适当的手段治疗人类疾病 。
Human stem cell is a unique cell population with the ability of self renewal and differentiation. There are many types of stem cells in human embryonic body and adult tissues, and they have crucial functions in human development. The stem cell differentiation is of great importance for the success of stem cell based therapies,whose effectiveness is determined by the intrinsic property of the cells and the cell microenvironment. The studies on the differentiation of human stem cell include the structural property of the cell and the molecular mechanism in vivo and in vitro . The aim of scientists is to gain the renewable and directional differential stem cells in vitro and use them for a variety of human diseases.
出处
《第二军医大学学报》
CAS
CSCD
北大核心
2003年第9期929-932,共4页
Academic Journal of Second Military Medical University
基金
国家自然科学基金重大项目 ( 90 2 0 80 2 6)
