摘要
目的 对比研究幽门螺杆菌 (Hp)阳性及阴性的消化性溃疡患者血清中IL - 2、IFN -γ的水平及其作用。方法 采用双抗体夹心ELISA法检测 2 3例Hp阳性及 14例Hp阴性消化性溃疡患者血清中IL - 2、IFN-γ的水平 ,观察Hp感染时此类细胞因子的变化。结果 Hp阳性组IL - 2、IFN -γ浓度明显低于Hp阴性组 (P <0 .0 5 ,P <0 .0 1)。结论 Hp感染的消化性溃疡患者细胞免疫下降。
Objective To contrastively study serum IL-2 and IFN-γ levels of patients with peptic ulcer whose Hp were positive or negative.Methods Serum IL-2 and IFN-γ levels were detected in 23 patients with peptic ulcer whose Hp were positive and 14 patients with peptic ulcer whose Hp were negative by means of double antibody ELISA method.Changes of these two cytokines were observed in patients infected with Helicobacter pylori.Results Serum IL-2 (P<0.05) and IFN-γ(P<0.01) levels were significantly lower in the Hp positive group than those in the Hp negative group.Conclusion Hp infection can decrease cytoimmunity of patients with peptic ulcer.
出处
《杭州医学高等专科学校学报》
CAS
2002年第3期78-79,共2页
Journal of Hangzhou Medical College
