摘要
目的——研究肝再生磷酸酶-3(PRL-3)在非小细胞肺癌(NSCLC)的表达及意义。方法——采用免疫组化法检测25例对照组和51例NSCLC患者PRL-3表达水平并进行分析比较。结果——PRL-3在对照组、肺癌组的阳性表达率分别为12.00%和74.51%(P【0.05);PRL-3的表达与非小细胞肺癌有无淋巴结转移及临床分期有关(p【0.05),与年龄、性别、病理类型无关(P】0.05)。结论——PRL-3表达与非小细胞肺癌的发生发展有一定的关系,PRL-3检测可作为判定非小细胞肺癌浸润及转移程度的一个生物学指标。
Objective-Study of phosphatase of regenerating liver-3(PRL-3) in non-small cell lung cancer(NSCLC) expression and significance.Methods-were detected by immunohistochemical staining in 25 cases of the control group and 51 cases of NSCLC patients,the expression level of PRL-3 and comparative analysis.Results--the positive expression of PRL-3 in the control group,the lung cancer group were 12%and 74.51%(P < 0.05);and the expression of PRL-3 in non small cell lung cancer with and without lymph node metastasis and clinical stage(P < 0.05),regardless of age,gender,pathological type(P > 0.05).There is a certain relationship between the occurrence and development of conclusion--and the expression of PRL-3 in non small cell lung cancer,PRL-3 detection can be used as a biological indicator to determine non small cell lung cancer invasion and metastasis degree.
出处
《铜仁职业技术学院学报》
2014年第2期31-34,共4页
Academic forum of Tongren Polytechnic College
关键词
非小细胞肺癌
肝再生磷酸酶-3
免疫组化
non small cell lung cancer
-3 phosphatase of regenerating liver
immunohistochemistry
