摘要
目的 :探讨低密度脂蛋白胆固醇 (LDL C) /高密度脂蛋白胆固醇 (HDL C)及甘油三酯 /HDL C比值与冠心病的关系。 方法 :检测 3 42例经冠状动脉造影确诊的冠心病患者 (冠心病组 )和 2 0 2例冠状动脉造影正常者 (对照组 )的血脂中总胆固醇、甘油三酯、LDL C及HDL C含量 ,计算LDL C /HDL C及甘油三酯 /HDL C的比值。 结果 :与对照组相比 ,冠心病患者的总胆固醇、LDL C及LDL C/HDL C比值明显增高 ,HDL C显著降低 ,有显著性差异 (P <0 0 5～ 0 0 0 1) ,而甘油三酯及甘油三酯 /HDL C比值两组间无显著差别。多元回归分析显示 ,冠心病的危险性与LDL C/HDL C比值呈正比 ,与甘油三酯及甘油三酯 /HDL C比值无显著相关。 结论 :LDL C/HDL C比值对冠心病有一定的预测价值 ,而甘油三酯 /HDL C比值的预测价值尚待研究。
Objective: To investigate the relationship of low density lipoprotein-cholesterol(LDL-C)/ high density lipoprotein-cholesterol(HDL-C) ratio, triglyceride /HDL-C ratio to coronary heart disease(CHD). Methods: Five handred and forty-four patients with suspected CHD were studied by the case-control method, who were divided into two groups according to the results of coronary arteriography: ①CHD group (n=342) and ② non-CHD group (n=202). The patient’s serum lipids were detected by the standard method. Results: Compared with non-CHD group, total cholesterol, LDL-C level and LDL-C/HDL-C ratio were significantly elevated, but HDL-C level was significantly lowered in the CHD group. There was no statistical difference in triglyceride and triglyceride /HDL-C ratio between groups. Multiple stepwise regression analysis showed that CHD risk was positively correlated with LDL-C/HDL-C ratio, but not correlated with triglyceride /HDL-C ratio. Conclusion: LDL-C /HDL-C ratio is a good predicator for CHD. The predicative value of triglyceride /HDL-C ratio remains to be studied.
出处
《中国循环杂志》
CSCD
北大核心
2003年第4期273-275,共3页
Chinese Circulation Journal
