摘要
目的 回顾性分析评价诱导化疗在中晚期舌癌治疗中的作用。方法 收集我院 1992～ 1999年间收治的病例及随访资料完整的中晚期舌癌 6 5例 ,其中单纯手术治疗组 2 7例 ,综合治疗组 38例。综合治疗包括平阳霉素单药诱导病例 2 2例 ,长春新碱 +甲氨喋呤 (VM )方案诱导化疗病例 16例 ,诱导化疗后 2～ 3周行舌癌根治术。结果 5年生存率单纯手术组为 4 4 .4 % ,综合治疗组为 5 0 % ;复发率则分别为 39.3%和 31.9% ,两组比较无统计学意义。
Objective To analyze the role of inducing chemotherapy for patients with advanced tongue squamous cell carcinoma (SCC).Methods Sixty five cases of advanced tongue SCC were collected,there were 27 cases treated by surgery alone,38 cases were treated with inducing chemotherapy,including 22 cases treated with pinyangmycin alone and 16 cases treated with vincristine+methotrexate (VM) chemotherapy,then all of those cases were treated with surgery.Results Five year survival rate was 44.4% of the surgery group and 50% of combination therapy group;the recurrence rate was 39.3% and 31.9% respectively.Conclusion Inducing chemotherapy could not prolong the 5 year survival rate.
出处
《现代口腔医学杂志》
CAS
CSCD
2003年第5期452-453,共2页
Journal of Modern Stomatology
