摘要
目的反复多次化疗的晚期肿瘤患者的癌性贫血是临床上治疗的难点,通过分析这些患者的血清促红细胞生成素(EPO)的水平,指导临床治疗以提高患者的生存质量。方法对38例癌性贫血患者用ELISA进行血浆EPO的检测。结果24例患者血浆EPO高于正常值,仅1例低于正常值。讨论EPO是调节哺乳动物红细胞生成的主要因子,晚期癌性贫血患者的EPO血清水平正常或高于正常,说明机体的自身调整功能强大,对于临床治疗上EPO的应用有重要的指导意义。
Objective To explore the clinical significance of serum erythropoietin (EPO) detection in patients with cancer-re-lated anemia for improving the life quality of the cancer patients in advanced stage with repeated chemotherapy. Method The serum EPO levels were determined in 38 cases of cancer-related anemia with enzyme-linked immunosorbent assay (ELISA). Results In 24 patients, the serum EPO level was elevated above the normal range, and lowered EPO level was detected in on-ly 1 cases. Conclusion Normal or elevated serum EPO level in patients with cancer-related anemia indicates strong abilities of the patients in self regulation, having important clinical implications for the use of EPO.
出处
《第一军医大学学报》
CSCD
北大核心
2003年第9期954-955,共2页
Journal of First Military Medical University
