体外培养的神经嵴细胞的定向诱导分化
摘要
神经嵴细胞是发育中具有多向分化潜能的干细胞,可向神经元、神经胶质细胞、软骨细胞、平滑肌细胞和黑色素细胞等多方向分化。其分化受到多种因子和化学物质的影响,包括转录因子、生长因子、钙离子浓度和细胞外基质等。
出处
《口腔医学》
CAS
2003年第5期306-308,共3页
Stomatology
参考文献23
-
1Howard M, Foster DN, Cserjesi P. Expression of HAND gene products may be sufficient for the differentiation of avian neural crest-derived cells into catecholaminergic neurons in culture [J]. Dev Bion, 1999,215( 1 ) :62-77.
-
2Lo L, Sommer L, Anderson DJ. MASH1 maintains competence for BMP2-induced neuronal differentiation in post-migratory, neural crest cells [J] .Curr Biol,1997,7(6) :440 -450.
-
3Wu X, Howard MJ. Two signal transduction pathways involved in the catecholainergic differentiation of avian neural crest - derived cells in vitro [J].Mol Cell Neurosci, 2001,18(4):394-406.
-
4Bilodeau ML, Boulineau T, Greulich JD, et al. Differential expresstion of sympathyoadrenal lineage- determinging genes and phenotypic markers in cultured primary neural crest cells [J]. In Vitro Cell Dev Biol Anim, 2001,37(3) : 185 - 192.
-
5Morrison SJ, Csete M, Groves AK, et al. Culture in reduced levels of oxygen promotes clonogenic sympathoadrenal differentiation by isolated neural crest stem cells [J] .J Neurosci ,2000,20(19) :7370 - 7376.
-
6White PM, Morrison SJ,Orimoto K, et al. Neural crest stem cells undergo cell - intrinsic developmental changes in sensitivity to instructive differentiation signals. [J] .Neuron, 2001,29(1):57-71.
-
7Murphy M, Reid K, Ford M,et al. FGF2 regulates proliferation of neural crest cells, with subsequent neuronal differentiation regulated by LIF or related factor [J]. Development, 1994,120(12) :3519 - 3528.
-
8Brill G, Vaisman N, Neufeld G, et al, BHK-21-derived cell lines that produce basic filbroblast growth factor, but not parental BHK-21 cells,initiate neuronal differentiation of neural crest progenitor [J]. Development, 1992,115(4) : 1059 - 1069.
-
9Giannini G, Alesse E, Di Marcotullio L, et al. EGF regulates a complex pattern of gene expression and represses smooth muscle differentiation during the neurotypic conversion of the neual-crest-derived TC-1S cell line [J].Exp Cell lies, 2001,264(2):353-362.
-
10Pinco O, Carmeli C, Rosenthal A, et al. Neurotrophin-3 affects proliferation and differentiation of distinct nauralcrest cells and is present in the early neural tube of avian embryons[J] .J Neurobiol, 1993,24(12) : 1626 - 1641.
-
1张小云,罗振国,曾弥白.NPY样免疫反应在蝾螈发育过程中神经系统的定位研究[J].实验生物学报,2000,33(1):41-51.
-
2耿丹丹,崔慧先,张三兵,王磊,康林,苏玉红.背侧抑制性轴突导向蛋白抑制鸡胚脊髓神经嵴细胞的迁移[J].神经解剖学杂志,2013,29(4):355-359. 被引量:4
-
3细胞疗法成功控制小鼠癫痫发作[J].生物学教学,2013,38(10):76-77.
-
4刘奔,李兰英,庞智玲.干细胞因子和受体在神经系统中的表达及其生物学效应[J].生理科学进展,2001,32(2):143-145. 被引量:1
-
5杨春玲,郝甜甜,李强飞,陈婷,毛华明,邓卫东.成黑色素细胞生成过程中信号调节的研究进展[J].中国畜牧兽医,2013,40(9):187-194. 被引量:8
-
6刘璋寅,沈尊理.周围神经中许旺细胞特异性标记物[J].组织工程与重建外科杂志,2012,8(5):292-297. 被引量:1
-
7石宇,赵树华,毛炳宇.Physical Blocking Neural Tube Closure Affects Radial Intercalation and Neural Crest Midline-directed Migration in Xenopus Dorsal Explants[J].Zoological Research,2009,30(6):639-644.
-
8张建平,段晓燕,周泽渊,赵文明,金岩.颌突外胚间充质干细胞(EMSCs)的体外分离及鉴定[J].中国生物工程杂志,2005,25(5):26-31. 被引量:1
-
9杨艳萍,武珊珊,景雅,李海荣,乔从进,张涛.小鼠胚胎细胞视黄酸结合蛋白1阳性神经嵴细胞的时空分布与功能[J].解剖学报,2013,44(4):519-524. 被引量:2
-
10武姗姗,景雅,杨艳萍,李海荣,乔从进,张涛,李凌飞.神经嵴细胞和胰岛因子1阳性细胞与小鼠胚胎心流出道发育的关系[J].解剖学报,2011,42(5):684-689. 被引量:8