摘要
目的 :建立肾泰脾康颗粒 (鹿茸、淫羊藿、肉苁蓉、黄柏等 )的质量标准。方法 :采用显微鉴别法对处方中鹿茸进行鉴别 ;采用薄层色谱法对处方中黄柏、山药、白术进行鉴别 ;采用HPLC色谱法对处方中地黄进行鉴别 ;采用HPLC法测定淫羊藿苷的含量。结果 :在显微镜下检出鹿茸 ;在TLC色谱中检出黄柏、山药、白术 ;在HPLC色谱中检出地黄 ;淫羊藿苷在 0 .10 4～ 0 .6 2 4 μg间呈良好的线性关系 ,r=0 .9998,平均回收率 10 0 .1% ,RSD为 1.3% (n =9)。结论 :所建立的鉴别法专属性强 ,定量方法简便、准确 ,可用于肾泰脾康颗粒的质量控制。
Objective: To establish the quality standard for Shentaipikang Granules (Cornu Cervi Pantotrichum, Herba Epimedii, Herba Cistanches, Cortex Phellodendri, etc). Methods: Counu Cervi Pantotrichum in this prescription was examined by microscopical identification. Cortex Phellodendri, Rhizoma Dioscoreae and Rhizoma Atractylodis Macrocephalae were identified by TLC. Radix Rehmanniae was identified by HPLC. Icariin was determined by HPLC. Results: Cornu Cervi Pantotrichum could be examined by microscopical identification, Cortex Phellodendri, Rhizoma Dioscoreae and Rhizoma Atractylodis Macrocephalae by TLC, and Radix Rehmanniae by HPLC. Icariin showed a good linear relationship at a range of 0.104 ～ 0.624 μg , r = 0.9998 . The average recovery was 100.1% and RSD was 1.3% ( n =9) respectively. Conclusion: These methods are simple, accurate and specific and can be used for the quality control of Shentaipikang Granules.
出处
《中成药》
CAS
CSCD
北大核心
2003年第10期798-801,共4页
Chinese Traditional Patent Medicine
