摘要
目的 探讨尾状核梗死的临床表现与局部脑血流 (rCBF)变化的关系。方法 对经CT及临床确定的 16例尾状核梗死病人进行SPECTrCBF定量显像 ,探讨rCBF变化与临床表现的关系。结果 16例病人患侧尾状核区rCBF为 ( 9.5 8± 2 .2 7)ml·10 0 g-1·min-1,明显低于正常对照组 (P <0 .0 5 ) ,其中 15例出现同侧皮层rCBF降低区 ,rCBF为 ( 2 5 .0 8± 10 .3 1)ml· 10 0g-1·min-1,明显低于正常对照组 (P <0 .0 5 )。 7例左侧皮层rCBF降低者中 ,4例伴失语 ,其rCBF为 ( 2 1± 2 .5 8)ml·10 0 g-1·min-1,3例无失语者rCBF为 ( 2 2 .67± 5 .92 )ml·10 0 g-1·min-1,两者无明显差别 (P >0 .0 5 )。 8例右侧皮层rCBF降低者中 ,4例伴忽视 ,其rCBF为 ( 2 0 .76± 4.17)ml·10 0g-1·min-1,无忽视者为 ( 3 3 .2 8± 14 .75 )ml·10 0g-1·min-1,两者比较差异明显 (P <0 .0 5 )。 10例意志丧失者病侧皮层rCBF为 ( 2 0 .41± 8.71)ml·10 0 g-1·min-1,明显低于正常对照组 (P<0 .0 5 )。结论 尾状核梗死可引起皮层rCBF的降低 ,皮层rCBF的降低与对侧空间忽视关系密切。
Objective To investigate the relationship between clinical manifestations of patients with caudate infarction and change of regional cerebral blood flow (rCBF). Methods Quantitative rCBF SPECT was performed in 16 patients with caudate infarction confirmed by CT and clinic. The relationship between rCBF change and clinical features was analysed. Results The rCBF of caudate regions infarcted in 16 cases were significantly lower than that of controls with average of (9.58± 2.27 )ml·100g -1 ·min -1 ( P <0.05),the rCBF of ipsilateral cortical regions in 15 cases were significantly lower than that of controls with average of (25.08±10.31)ml·100g -1 ·min -1 ( P <0.05). In 7 cases with left side cortical lesions, 4 were aphasia with cortical rCBF of (21±2.58)ml·100g -1 ·min -1 ,the cortical lesion rCBF of patients with nonaphasia were ( 22.67 ±5.92)ml·100g -1 ·min -1 . There was no significant difference between aphasia and non aphasia cases ( P >0.05). In 8 cases with right side cortical lesions, 4 with neglect were of cortical rCBF (20.76±4.17)ml·100g -1 ·min -1 , rCBF of patients without neglect were (33.28±14.75)ml·100g -1 ·min -1 ( P <0.05). The rCBF in cortical lesions of 10 patients with abulia were (20.41±8.71)ml·100g -1 ·min -1 , which was significantly lower than that of controls ( P <0.05). Conclusion Caudate infarction can lead to cortical rCBF reduction, which is closely related to contralateral spatial reglect.
出处
《中国医学影像技术》
CSCD
2003年第8期978-980,共3页
Chinese Journal of Medical Imaging Technology
