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α干扰素对慢性丙型肝炎患者血清肝纤维化指标的影响 被引量:3

Influence of interferon alpha on the serum fibrosis markers of chronic hepatitis C patients.
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摘要 丙型肝炎病毒(HCV)感染的最主要特征是慢性化,肝纤维化是这一慢性化过程中的一种极为重要的病变,因此,及早阻止肝纤维化的进程具有重要意义.
出处 《中华肝脏病杂志》 CAS CSCD 2003年第10期622-623,共2页 Chinese Journal of Hepatology
关键词 Α干扰素 慢性丙型肝炎 血清 肝纤维化指标 抗病毒 Hepatitis C virus Liver fibrosis Therapeutics Inter-feron
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  • 1李蕴铷,刘峰,徐道振,刀文彬,赵景民,陈红松,魏来.α干扰素治疗慢性丙型肝炎对肝纤维化的影响[J].肝脏,2006,11(2):119-120. 被引量:2
  • 2Tsukada S, Parsons CJ, Rippe RA. Mechanisms of liver fibrosis[J]. Clin Chim Acta, 2006, 364 (1 -2) : 33 -60.
  • 3Hemmann S, Graf J, Roderfeld M, et al. Expression of MMPs and TIMPs in liver fibrosis-a systematic review with special emphasis on anti-fibrotic strategies [ J ]. J Hepatol, 2007, 46 (5) : 955 - 975.
  • 4Mitsuda A, Suou T, Ikuta Y, et al. Changes in serum tissue inhibitor of matrix metdloproteinase-1 after interferon alpha treatment in chronic hepatitis C[J]. J Hepatol, 2000, 32(4): 666-672.
  • 5Bataller R,Brenner DA.Hepatic stellate cells as a target for the treatment of liver fibrosis[J].Semin Liver Dis,2001,21(3):437-451.
  • 6Olaso E,Friedman SL.Molecular regulation of hepatic fibrogenesis[J].J Hepatol,1998,29(5):836-847.
  • 7Nagase H,Woessner JF.Matrix metalloproteinases[J].J Biol Chem,1999,274(31):21 491-21 494.
  • 8Yashiji H,Kuriyama S,Yoshi J,et al.Tissue inhibitor of metalloproteinase-1 attenuates spontaneous liver fibrosis resolution in the transgenic mouse[J].Hepatology,2002,36(4):850-860.
  • 9Mitsuda A,Suou T,Ikuta Y,et al.Changes in serum tissue inhibitor of matrix metdloproteinase-1 after interferon alpha treatment in chronic hepatitis C[J].J Hepatol,2000,32(4):666-672.
  • 10中华医学会传染病与,寄生虫病学分会,肝病学分会.病毒性肝炎防治方案[J].中华肝脏病杂志,2000,8(6):324-329. 被引量:14012

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