摘要
目的观察中药藏茵陈对肝脏慢性炎症的治疗作用。方法慢性乙型肝炎患者43例,代偿期肝炎肝硬化患者17例。随机分为2组。治疗组给予常规保肝药物治疗及加用藏茵陈17.5mg,3/d,口服,对照组仅给予常规保肝药物治疗,疗程均3个月。治疗前、治疗后每月及治疗结束时分别检验血清 ALT、TBiL,并观察药物的不良反应。结果治疗1个月后,治疗组 ALT、TBiL 的平均水平与治疗前及对照组相比有显著差异,ALT 复常率与对照组相比也有显著差异,但 TBiL 的复常率与对照组相比无统计学意义。治疗结束时,治疗组与对照组相比.ALT 的平均水平及复常率均无显著差异,但 TBiL 的平均水平及复常率均有显著差异。2组均未见不良反应。结论藏茵陈在肝脏慢性炎症的治疗中有降酶、退黄的作用,随治疗时间的延长,促进 TBiL 水平下降的疗效表现更加明显。
Objective The effect of herbal medicine of zangyinchen was observed in the treatment of patients with chronic hepatitis B and liver cirrhosis caused by hepatitis virus.Methods A total of 43 cases with hepatitis B and 17 cases with liver cirrhosis were divided into two groups.Patients in group one were treated with conventional drugs and zangy- inchen (17.5mg,3/d) and those in group two were only treated with conventional drugs.ALT and TBiL was respective- ly measured pre-treatment,one month after treatment and at the end of the treatment.Results The level of ALT and TBiL one month after treatment have significantly difference in group one compared with the pre-treatment level and that in control group.At the same time,the normalized ratio of ALT in group one compared with that in control group were significantly increased.However,there were no significant difference in the normalized ratio of TBiL between the two groups.At the end of treatment,the level and the normalized ratio of ALT between the two groups were not signifi- cantly different,but the differences of TBiL were significant.No adverse response was observed in the two groups.Con- clusion The herbal medicine of zangyinchen can accelerate the decrease of the level of ALT and TBiL and the efficacy of therapy become obviously with time prolongation.
出处
《传染病信息》
2003年第3期132-133,共2页
Infectious Disease Information
