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60例成人慢性鼻窦炎需氧菌初步研究 被引量:3

Aerobes of chronic sinusitis on adults:report of 60 cases
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摘要 目的 研究成年慢性鼻窦炎患者窦口鼻道复合体作为一个整体的需氧菌情况。方法 选择 4 0例成年患者分为S(Ⅰ型组 )与P(Ⅱ型组 ) ,同时设正常对照组 2 0例 ,采集不同部位标本 ,进行需氧菌分离培养及药物敏感试验 ,比较阳性率、3个部位相同率、主要细菌等 3个指标。结果 对照组 2 0例阳性率低 ,在 4 0例 12 0个部位中共检出细菌 5 0例 ,分别归 9属 13种 ,主要为表皮葡萄球菌、类白喉棒状杆菌、流感嗜血杆菌、产气肠杆菌、金黄色葡萄球菌等。上述指标的比较两型间均无明显差别 ,但 3个部位则多不相同。大多对青霉素类、头孢菌素类、氨基甙类 (庆大霉素 )敏感 ,其中表皮葡萄球菌多数为耐甲氧西林菌株。结论 探讨了需氧菌在慢性鼻窦炎中的地位 ;从需氧菌角度 ,病变时的窦口鼻道复合体各部位之间存在一种割裂和彼此独立的状态 ;并对抗生素应用进行了分析。 Objective To explore the aerobes of ostiomeatal complex in chronic sinusitis of adults and to compare tyepⅠ(sinusitis) with typeⅡ(sinusitis with polyps).Methods Forty patients were grouped as S and P;twenty healthy adults have been also enrolled as control.We took samples at middle meatus,maxillary sinus and ethmoid sinus with swabs on each individual; cultivation,identification of aerobes and antibiotic susceptibility test performed consequently; positive rate,identical rate and major aerobes were compared after that.Results Aerobes were found in fifty sites which categoried to thirteen species in nine genera,main species were Staphylococcus epidermidis,diphtheroid corynebacterium,haemophilus influenzae,enterobacter aerogenes,staphylococcus aureus,etc.No significant differences existed in typeⅠ and typeⅡ,while the aerobes of three respective sites were different in these two groups.Most of the microorgnanisms were sensitive to penicillin V,cephalothin,aminoglycosides(gentamycin),while most of the S epidermidis were methicillin resistant.Conclusions The role of aerobes in chronic sinusitis were discussed;considering aerobes only,different parts of the ostiomeatal complex manifester separately in chronic inflammatory state;furthermore,antibiotic medication were analysed.
出处 《重庆医学》 CAS CSCD 2003年第11期1465-1466,共2页 Chongqing medicine
关键词 慢性鼻窦炎 需氧菌 细菌培养 抗生素敏感试验 ostiomeatal complex sinusitis aerobe bacterial cultivation antibiotic susceptibility test
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